Results 141 to 150 of about 14,230,992 (393)

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami   +4 more
wiley   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

open access: yesAdvanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang   +2 more
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi   +2 more
wiley   +1 more source

The Relationship Between Interleukin-4 Levels and Cardiovascular Events in Patients with Chronic Kidney Disease

open access: yesRisk Management and Healthcare Policy, 2020
Ling Gu,1 Huogen Liu,1 Xianhong Liu,2 Xi Zeng,3 Zuchen Lei,1 Xin Wan1 1Department of Critical Care Medicine, Mindong Hospital of Fujian Medical University, Fuan, Fujian 355000, People’s Republic of China; 2Department of Nephrology, Mindong Hospital
Gu L, Liu H, Liu X, Zeng X, Lei Z, Wan X
doaj  

Inhibition of Interleukin-4- and CD40-induced IgE Germline Gene Promoter Activity by 2′-Aminoethoxy-modified Triplex-forming Oligonucleotides [PDF]

open access: hybrid, 2001
Adrian M. Stütz   +4 more
openalex   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen   +6 more
wiley   +1 more source

Interleukin-4 transgenic mice develop glomerulosclerosis independent of immunoglobulin deposition [PDF]

open access: bronze, 2000
Beate M. Rüger   +5 more
openalex   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad   +7 more
wiley   +1 more source

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