Results 171 to 180 of about 705,101 (300)

Regulation of interleukin‐4 activity by soluble interleukin‐4 receptors

Journal of Clinical Laboratory Analysis, 1995
K, Enssle, G, Schulz
openaire   +2 more sources

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

Advanced Science, EarlyView.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz, Luana C. Soares, Gretchen Greene, Fernando Messore, Mohammed Abuelem, Mingyu Li, Caroline Andersen, Mirriam Domocos, Elisa Vitiello, Rabeah Abdul Razak, Marlene Lawston, Gabriel Moser, Talia Vasaturo‐Kolodner, Mona Barkat, Roslyn M. Bill, Edward Mann, Linna Zhou, Mootaz M. Salman, Hagan Bayley, Zoltán Molnár, Francis G. Szele   +20 more
wiley   +1 more source

Contribution of Interleukin-4 Promoter Genotypes to Gastric Cancer Risk in Taiwan. [PDF]

In Vivo
Fu CK, Lee HT, Yang YC, Chen JC, Yang MD, Wang YC, Shih HY, Tsai CW, Bau DT, Chang WS.   +9 more
europepmc   +1 more source

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

Advanced Science, EarlyView.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben, Charitha C. Anamala, Sahan B. S. Kansakar, Vaishnavi Koduri, Volha Liaudanskaya   +4 more
wiley   +1 more source

Interleukin-4-mediated Pro-Regenerative Cellular Reprogramming in 3-dimensional Liver Culture. [PDF]

Cell Mol Gastroenterol Hepatol
Camat D, Nakib D, Chung SW, Sekhon M, Liu Y, Lumanto P, Hyduk SJ, Perciani CT, Bartczak AM, Cheng ML, Pezzutti OI, Kaltagian M, Altaf F, Jafari SM, Manuel J, Thoeni C, Ogawa S, Ma XZ, McGilvray ID, MacParland SA.   +19 more
europepmc   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Human interleukin-4-dependent facilitation of human IgG production in PBL-NOG-hIL-4-Tg mice. [PDF]

Front Immunol
Kametani Y, Ohshima S, Ito R, Ohno Y, Yamada S, Hoshino Y, Miyamoto A, Suzuki-Ohno M, Katano N, Tsuda B, Miyazawa M, Kashiwagi H, Kirigaya D, Shimizu T, Kojima M, Kikuchi Y, Nakada S, Ohki R, Yasuda A, Hirota A, Nakamura Y, Kulski JK, Mabuchi T, Ishimoto H, Shiina T.   +24 more
europepmc   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Characterization of the circRNA Landscape in Interleukin-4 Induced Anti-Inflammatory Microglia. [PDF]

Biomedicines, 2023
Li C, Wang H, Tang Y, Wu J.
europepmc   +1 more source

Cancer‐Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

Advanced Science, EarlyView.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are the predominant stromal components within the tumor microenvironment (TME), playing multifaceted roles in cancer progression through dynamic interactions with neoplastic and immune cells. Emerging evidence has revealed remarkable heterogeneity and plasticity of CAFs, which originate from diverse ...
Rujiao Liu, Lili Su, Shuiping Gao, Wenting Liu, Hongxia Wang   +4 more
wiley   +1 more source