Results 141 to 150 of about 14,492,078 (303)
Scientific ReportsBariatric surgery is an approved treatment for obesity that consistently improves metabolic syndrome, with well-documented beneficial effects on dyslipidemia, cardiovascular risk, nonalcoholic fatty liver disease and glucose homeostasis.
Maryam Mahjoubin-Tehran +6 more
doaj +1 more source
Interleukin-4 receptor pathway in neurons
, 2018 Multiple sclerosis (MS) is a chronic demyelinating inflammatory disease of the central nervous system (CNS) and belongs to the most frequent causes of irreversible disability in younger people. During the disease course of MS and the corresponding animal model experimental autoimmune encephalomyelitis (EAE), both adaptive and innate immune cells ...
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão +5 more
wiley +1 more source
Advanced Materials, EarlyView.A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh +11 more
wiley +1 more source
Interleukin-4 (IL-4) and Interleukin-4 Receptor Alpha Chain (IL-4Rα) Gene Polymorphisms in Egyptian Rheumatic Arthritis Patients [PDF]
Egyptian Journal of Pure and Applied Science, 2015 doaj +1 more source
Electropolymerized Aptasensor for Femtogram‐Level Cytokine Detection
Advanced Materials, EarlyView.Electropolymerization of 3‐amino‐ʟ‐tyrosine creates ultrathin, smooth, and chemically robust pALT nanofilms with accessible carboxyl functionalities for direct aptamer immobilization. Integrated with fiber‐optic SPR and OECT platforms, these interfaces enable IL‐6 detection down to 100 fg mL−1 and provide a versatile route to bioelectronic sensing ...
Jiyao Yu +7 more
wiley +1 more source
Evolution and function of interleukin-4 receptor signaling in adaptive immunity and neutrophils. [PDF]
Genes Immun, 2020 Heeb LEM, Egholm C, Boyman O.
europepmc +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Association between the polymorphisms of interleukin-4, the interleukin-4 receptor gene and asthma.
Chinese medical journal, 2014 Interleukin-4 (IL4) is one of the most important cytokines involved in a variety of allergic disorders, particularly, asthma. A number of genetic epidemiological studies have identified an association between the gene polymorphisms of IL4 and interleukin-4 receptor (IL4R) and asthma in different populations.
Ning, Zhu +7 more
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