Results 101 to 110 of about 9,333,661 (382)
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2019 Background Systemic inflammation is a strong predictor of atrial fibrillation. A key role for electrical remodeling is increasingly recognized, and experimental data suggest that inflammatory cytokines can directly affect connexins resulting in gap ...
P. Lazzerini +15 more
semanticscholar +1 more source
Circulating interleukin-6 receptor in patients with sepsis syndrome [PDF]
, 1995 Item does not contain ...
Clement, C. +6 more
core +2 more sources
FEBS Open Bio, EarlyView.Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
wiley +1 more source
Interleukin-6 Signaling Pathway and Its Role in Kidney Disease: An Update
Frontiers in Immunology, 2017 Interleukin-6 (IL-6) is a pleiotropic cytokine that not only regulates the immune and inflammatory response but also affects hematopoiesis, metabolism, and organ development.
H. Su, Chuntao Lei, Chun Zhang
semanticscholar +1 more source
Regulation of anti-inflammatory gene expression in vascular endothelial cells by EPAC1 [PDF]
, 2015 Suppressor of cytokine signalling 3 (SOCS3) is a potent inhibitor of pro-inflammatory pathways involved in atherogenesis and the development of neo-intimal hyperplasia (NIH), which contributes to the in-stent re-stenosis responsible for the failure of ...
Palmer, Timothy P., Yarwood, Stephen J.
core +1 more source
Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
FEBS Open Bio, EarlyView.Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source
Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis
Circulation, 2019 Supplemental Digital Content is available in the text. Background: Clonal hematopoiesis of indeterminate potential (CHIP) refers to clonal expansion of hematopoietic stem cells attributable to acquired leukemic mutations in genes such as DNMT3A or TET2 ...
A. Bick +8 more
semanticscholar +1 more source
The role of IL-6 for predicting neonatal sepsis: A systematic review and meta-analysis [PDF]
, 2011 Objective: Neonatal sepsis (NS) is a common and life-threatening disorder in infants. Previous studies showed that interleukin-6 (IL-6) may be a valid non-invasive and rapid method for diagnosis of NS.
Ahani, A. +4 more
core +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
The pathophysiological profile of interleukin-6 and anti-interleukin-6 antibody
El Mednifico Journal, 2013 Interleukin-6 is a multifunctional cytokine produced by variety of cells including tumor cells. It is produced by monocytes, macrophages, B-cells and T-cells. Interleukin-6 stimulates platelet production through thrombopoietin. Interleukin-6 in surplus amount is also produced by epithelial ovarian cancer cells.
Mushtaq Ahmed, Rafaqat Bota
openaire +2 more sources