Therapeutic targets in rheumatoid arthritis: the interleukin-6 receptor [PDF]
, 2017 RA is a chronic, debilitating disease in which articular inflammation and joint destruction are accompanied by systemic manifestations including anaemia, fatigue and osteoporosis.
Choy, Ernest, Dayer, Jean-Michel
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Diphlorethohydroxycarmalol Inhibits Interleukin-6 Production by Regulating NF-κB, STAT5 and SOCS1 in Lipopolysaccharide-Stimulated RAW264.7 Cells [PDF]
, 2015 Na-Jin Kang +9 more
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Advanced Functional Materials, EarlyView.xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
IL-6 Signaling in Immunopathology: From Basic Biology to Selective Therapeutic Intervention
ImmunoTargets and TherapyTim Schumertl, Juliane Lokau, Christoph Garbers Institute of Clinical Biochemistry, Hannover Medical School, Hannover, 30625, GermanyCorrespondence: Christoph Garbers, Institute of Clinical Biochemistry, Hannover Medical School, Carl-Neuberg-Strasse 1 ...
Schumertl T, Lokau J, Garbers C
doaj
Interleukin-6: Molecular Pathophysiology
Journal of Investigative Dermatology, 1990 The cytokine interleukin-6 (IL-6) has emerged as a major systemic alarm signal which appears to be produced by essentially every injured tissue. Recent evidence points to the skin, particularly the injured skin, as one of the major sites of IL-6 production.
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Advanced Healthcare Materials, EarlyView.Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier +7 more
wiley +1 more source
Prostaglandin‐Independent Stimulation of Interleukin‐6 Production by Fibrinogen Degradation Product D in Perfused Murine Liver [PDF]
, 1998 Miklós Csala +8 more
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Advanced Healthcare Materials, EarlyView.A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim +16 more
wiley +1 more source
PENGARUH OLAHRAGA PERNAFASAN TERHADAP PERUBAHAN KADAR BETA ENDORPHIN, INTERLEUKIN-2, INTERLEUKIN-4, INTERLEUKIN-6, IMUNOGLOBULIN G, dan HORMON KORTISOL (Sebuah Kajian Imunologi Pada Aktivitas Fisik) [PDF]
, 2007 The purpose of the research to expressing the changing of immunity at breathing exercise. This research represent of experimental. Device used “randomized pretest-posttest control group design. Population is student M A Mu'Alimin Yogyakarta.
Rumpis Agus Sudarko, M. S
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IL6 and IL6R as Prognostic Biomarkers in Colorectal Cancer
BiomoleculesColorectal cancer is the third most diagnosed malignancy worldwide and survival outcomes remain poor. Research is focused on the identification of novel prognostic and predictive biomarkers to improve clinical practice.
Kathryn A. F. Pennel +10 more
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