Results 31 to 40 of about 8,039,165 (298)

The Interleukin-8 Pathway in Cancer [PDF]

open access: yesClinical Cancer Research, 2008
Abstract Interleukin-8 (IL-8) is a proinflammatory CXC chemokine associated with the promotion of neutrophil chemotaxis and degranulation. This chemokine activates multiple intracellular signaling pathways downstream of two cell-surface, G protein–coupled receptors (CXCR1 and CXCR2).
Waugh, David J.J., Wilson, Catherine
openaire   +3 more sources

Characterization of Interleukin 8 in Woodchucks with Chronic Hepatitis B and Hepatocellular Carcinoma

open access: yes, 2010
The eastern woodchuck, Marmota monax, represents a useful animal model to study hepatitis B virus infection in humans. However, immunological studies in this model have been impeded by a lack of basic information about the components of the immune system
劉俊人;郭敏玲;黃璟隆;陳定信;陳培哲;吳慧琳   +1 more
core   +1 more source

Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding [PDF]

open access: yes, 2009
Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk factors that include hypertension and hyperlipidaemia, influenced by diet.
Dower, S.   +25 more
core   +1 more source

Effect of green tea extract on expression of proteins involved in drug transport and metabolism and on the expression and secretion of the chemokine interleukin-8 in intestinal cell lines [PDF]

open access: yes, 2006
Pharmacokinetic interactions often occur as a result of changes in the functional expression of drug-metabolising and transporting proteins. In recent years, interactions of herbal medicines with synthetic drugs have come into focus and drug-interactions
Netsch, Marco Ivo
core   +1 more source

Evaluation of Recombinant Bovine Interleukin-8 (rbIL-8) as a Treatment for Chronic Intramammary Infection in Dairy Cows

open access: yesAntibiotics, 2022
Mastitis is one of the main contributors to antimicrobial resistance in livestock, so alternative therapies are being investigated to address it. The present study assessed the capability of recombinant bovine interleukin-8 (rbIL-8) to improve neutrophil
Phillip M. G. Peixoto   +7 more
doaj   +1 more source

Relationship between interleukin 6 and 8 with Semen characteristics in fertile patients

open access: yesBiobacta Journal of Biochemistry and Molecular Biology
Infertile males were tested for the presence of interleukin-6 and interleukin-8, as well as lipid peroxidation in their sperm. A total of 75 infertile men, including 15 fertile men, were used as controls, with semen samples collected by masturbation ...
Hayder Al-Msaid, Hydar Khalfa, Hasan Ali
doaj   +1 more source

Evaluation of Serum Interleukins-6, 8 and 10 Levels as Diagnostic Markers of Neonatal Infection and Possibility of Mortality [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2013
Objective(s): Bacterial infection contributes substantially to neonatal morbidity and mortality. Early diagnosis of neonatal sepsis is difficult because clinical signs are non-specific.
Hassan Boskabadi   +8 more
doaj  

Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages [PDF]

open access: yes, 2009
Background Toll-like receptors (TLRs) are present on monocytes and alveolar macrophages that form the first line of defense against inhaled particles.
Esmaeil Mortaz   +23 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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