Results 181 to 190 of about 1,297,479 (340)

Experience with the Use of High-Dose Interleukin-2 in the Treatment of 652 Cancer Patients

, 1989
Steven A. Rosenberg, Michael T. Lotze, James Chih‐Hsin Yang, Paul Aebersold, W. Marston Linehan, Claudia A. Seipp, Donald E. White   +6 more
openalex   +2 more sources

Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia. [PDF]

, 1989
Yuman Fong, Kevin J. Tracey, Lyle L. Moldawer, David Hesse, K Manogue, J S Kenney, A T Lee, George Kuo, A. C. Allison, S. F. Lowry   +9 more
openalex   +1 more source

Fibronectin Fibers Progressively Lose Their Tension in Invasive Human Breast Carcinoma while Being Tensed in DCIS and Healthy Breast Tissue

Advanced Science, EarlyView.
Extracellular matrix remodeling is crucial in cancer progression. Using a peptide to probe the tension of ECM fibers, it was found that Fibronectin fibers gradually lose tension as human breast carcinoma progresses, while their tension is maintained in ductal carcinoma in situ (DCIS), the non‐invasive precursor of breast cancer. This loss of tension is
Arnaud Miéville, Charlotte M. Fonta, Cornelia Leo, Lucine Christe, Jörg Goldhahn, Gad Singer, Viola Vogel   +6 more
wiley   +1 more source

Human recombinant interleukin 4 induces Fc epsilon R2/CD23 on normal human monocytes. [PDF]

, 1988
Donata Vercelli, Haifa H. Jabara, B W Lee, Narelle Woodland, R S Geha, Donald Y.M. Leung   +5 more
openalex   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Toxicity and therapeutic efficacy of high-dose interleukin 2. In vivo infusion of antibody to NK-1.1 attenuates toxicity without compromising efficacy against murine leukemia. [PDF]

, 1989
David Peace, Martin A. Cheever
openalex   +1 more source

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen   +21 more
wiley   +1 more source

Corrigendum: Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine-3, and NLRP3-MyD88-chemokine pathways

Frontiers in Cardiovascular Medicine, 2023
Vincenzo Quagliariello, Margherita Passariello, Margherita Passariello, Annabella Di Mauro, Ciro Cipullo, Andrea Paccone, Antonio Barbieri, Giuseppe Palma, Antonio Luciano, Simona Buccolo, Irma Bisceglia, Maria Laura Canale, Giuseppina Gallucci, Alessandro Inno, Claudia De Lorenzo, Claudia De Lorenzo, Nicola Maurea   +16 more
doaj   +1 more source

Exploring the causal relationship between interleukin levels and osteoarthritis: A two-sample Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Wu Z, Zhou H, Wu Z, Hou Z.
europepmc   +1 more source

Efficacy of interleukin-1 beta against systemic Candida albicans infections in normal and immunosuppressed mice [PDF]

, 1989
R A Pecyk, E B Fraser-Smith, Thomas R. Matthews   +2 more
openalex   +1 more source