Results 201 to 210 of about 697,588 (247)

Modulation of IRAK4 as a therapeutic strategy against monosodium urate- and xanthine-induced inflammation in macrophages and HepG2 cells. [PDF]

Front Immunol
Umar S, Chang HT, Maienschein-Cline M, Ravindran S.   +3 more
europepmc   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Plasma IL-6, IL-8 and IL-10 as predictors of response to PD-1 blockade immunochemotherapy in advanced gastric cancer. [PDF]

Clin Exp Med
Yang F, Yao J, Tong X, Luo X, Liu Q, Zhu W.   +5 more
europepmc   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

Predictive Biomarker for Cardiac Surgery-Associated Acute Kidney Injury: A Retrospective Analysis. [PDF]

Braz J Cardiovasc Surg
Zhang B, Zhang D, Wang S, Yu H.
europepmc   +1 more source

IRAK1 promotes gastric cancer progression by activating the PI3K/AKT/mTOR pathway and inducing the M2 polarization of tumor-associated macrophages. [PDF]

Chin Med J (Engl)
Huang J, Wu X, Feng Y, Yang A.
europepmc   +1 more source

Nutritional Modulation of the Gut-Kidney Axis. [PDF]

Nutrients
Bogdan RG, Gligor FG, Anderco P, Popa LM, Popescu A, Bloanca VA, Leonte E, Iliescu Glaja M, Crainiceanu ZP, Ichim C.   +9 more
europepmc   +1 more source

Interleukin 4, Interleukin 13, and Interleukin 9

Interleukin 4, Interleukin 13, and Interleukin 9
openaire