Results 231 to 240 of about 1,297,479 (340)

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

A case of primarily facial pyoderma gangrenosum associated with Takayasu arteritis

JAAD Case Reports, 2017
Ken Okamura, MD, PhD, Takayuki Konno, MD, PhD, Kosuke Onami, MD, Mariko Nikaido, MD, Naoko Okazaki, MD, Yuko Abe, MD, PhD, Masahiro Hayashi, MD, PhD, Yoriko Yaguchi, MD, Hiroko Sato, MD, Tsuneo Konta, MD, PhD, Tamio Suzuki, MD, PhD   +10 more
doaj   +1 more source

Therapeutic Landscape of Rosacea: From Clinical Trials to Future Directions. [PDF]

J Cosmet Dermatol
Li S, Lin J, Li J, Mo X, Ju Q.
europepmc   +1 more source

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics

Advanced Science, EarlyView.
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen, Qiyan Guo, Hong Li, Xue Chi, Xiang Ma, Yanqiong Tang, Quanfeng Liang, Zhu Liu, Yong Liu, Juanjuan Li   +9 more
wiley   +1 more source

The Predictive Value of Tumor Necrosis Factor Receptor-Associated Factor-Interacting Protein With Forkhead-Associated Domain (TIFA) and Interleukin-1 Beta in Sepsis-Associated Acute Kidney Injury: Bioinformatics Analysis and Experimental Validation. [PDF]

Cureus
Zhao Z, Guo W, Zhao B, Ma L.
europepmc   +1 more source

A broad-host-range expression vector based on the pL promoter of coliphage lambda: regulated synthesis of human interleukin 2 in Erwinia and Serratia species [PDF]

, 1987
Ronny Leemans, E. Remaut, Walter Fiers
openalex   +1 more source

In Situ Proliferating Peptide Nanoparticle Augments Multi‐Target Intervention of Secondary Brain Damage Following Subarachnoid Hemorrhage

Advanced Science, EarlyView.
This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang, Peisen Yao, Fuxiang Chen, Shufa Zheng, Xuegang Niu, Haojie Wang, Yuanxiang Lin, Bin Gao, Dezhi Kang   +8 more
wiley   +1 more source

Interleukin-2 Receptor as a Marker of Oxidative Stress in Paediatric Patients with Chronic Kidney Disease or Hypertension. [PDF]

Children (Basel)
Marčun Varda N, Močnik M, Filipič M, Homšak E, Svetej M, Golob Jančič S.   +5 more
europepmc   +1 more source

Induction of lymphokine-activated killer cytotoxicity with interleukin-2 and tumor necrosis factor-? against primary lung cancer targets

, 1989
Stephen C. Yang, Laurie B. Owen‐Schaub, Elizabeth A. Grimm, Jack A. Roth   +3 more
openalex   +1 more source

Lymphocytes expressing type 3 complement receptors proliferate in response to interleukin 2 and are the precursors of lymphokine-activated killer cells. [PDF]

, 1988
J. Dixon Gray, David A. Horwitz
openalex   +1 more source