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Interleukin-8 and Interleukin-17 for Cancer
Cancer Investigation, 2014Pro-inflammatory cytokines have been associated with chronic inflammation and inflammatory diseases. Increased levels of interleukins (ILs) have been associated with inflammatory disease exacerbation. ILs levels have been observed to be associated with advance stage cancer for several types of cancer and a poor prognostic maker for malignant disease ...
Nikolaos Katsikogiannis +5 more
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Interleukin 1 is more than an interleukin
Immunology Today, 1982Gery and co-workers(1) first described lymphocyte activating factor (LAF) in 1972, as an activity produced by cultured human peripheral blood adherent leukocytes which was directly mitogenic for murine thymocytes but not for immunocompetent peripheral lymphocytes.
Igal Gery, Joost J. Oppenheim
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Developmental & Comparative Immunology, 2004
As the adaptive immune system arose in jawed vertebrates, a reasonable working hypothesis is that cytokines involved exclusively in controlling the adaptive immune system, e.g. T1 and T2 cytokines, will only be found in jawed vertebrates whilst those with a role in innate responses, e.g.
Peter K. Kaiser +3 more
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As the adaptive immune system arose in jawed vertebrates, a reasonable working hypothesis is that cytokines involved exclusively in controlling the adaptive immune system, e.g. T1 and T2 cytokines, will only be found in jawed vertebrates whilst those with a role in innate responses, e.g.
Peter K. Kaiser +3 more
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Critical Care Medicine, 2020
Chemokines are chemotactic cytokines, and interleukin (IL)-8 represents the prototypical chemokine. As the name chemokine indicates, IL-8 is responsible for inducing chemotaxis, which is the directed migration of cells to a site of inflammation ...
D. Remick
semanticscholar +1 more source
Chemokines are chemotactic cytokines, and interleukin (IL)-8 represents the prototypical chemokine. As the name chemokine indicates, IL-8 is responsible for inducing chemotaxis, which is the directed migration of cells to a site of inflammation ...
D. Remick
semanticscholar +1 more source
New England Journal of Medicine, 1987
We studied the effects of adoptive immunotherapy with lymphokine-activated killer (LAK) cells plus interleukin-2 or therapy with high-dose interleukin-2 alone in 157 patients with metastatic cancer for whom standard therapy had proved ineffective or no ...
S. Rosenberg +12 more
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We studied the effects of adoptive immunotherapy with lymphokine-activated killer (LAK) cells plus interleukin-2 or therapy with high-dose interleukin-2 alone in 157 patients with metastatic cancer for whom standard therapy had proved ineffective or no ...
S. Rosenberg +12 more
semanticscholar +1 more source
Developmental & Comparative Immunology, 2011
Interleukins are a subgroup of cytokines, molecules involved in the intercellular regulation of the immune system. The term interleukin was first coined in 1979 to refer to molecules that signal between different leucocyte types, although not exclusively restricted to leucocyte communication.
Secombes, Christopher J. +2 more
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Interleukins are a subgroup of cytokines, molecules involved in the intercellular regulation of the immune system. The term interleukin was first coined in 1979 to refer to molecules that signal between different leucocyte types, although not exclusively restricted to leucocyte communication.
Secombes, Christopher J. +2 more
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Acta Clinica Belgica, 1987
SummaryDiscovered in 1976, the lymphokine interleukin-2, intensively studied during the last years, plays a major role in the regulation of the immune function. The authors reviewing its principal properties, anticipate forthcoming prospects of considerable implications in therapy.Acta Clin. Bclg. 42, 4: 255–68.
M. Hiden, P. Neve
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SummaryDiscovered in 1976, the lymphokine interleukin-2, intensively studied during the last years, plays a major role in the regulation of the immune function. The authors reviewing its principal properties, anticipate forthcoming prospects of considerable implications in therapy.Acta Clin. Bclg. 42, 4: 255–68.
M. Hiden, P. Neve
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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.
Science, 1997BAD is a distant member of the Bcl-2 family that promotes cell death. Phosphorylation of BAD prevents this. BAD phosphorylation induced by interleukin-3 (IL-3) was inhibited by specific inhibitors of phosphoinositide 3-kinase (PI 3-kinase).
L. Peso +4 more
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Interleukin-1α, Interleukin-1β, and Interleukin-1Ra Polymorphisms in Febrile Seizures
Journal of Child Neurology, 2005Febrile seizures are the most common form of childhood seizures. The exact mechanism promoting convulsions during a common febrile illness remains unknown, but it is accepted that genetic influences are likely to account for at least some of the cases.
Ozgur Tosun +5 more
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Physiologic roles of interleukin-2, interleukin-4, and interleukin-7
Current Opinion in Hematology, 1996The use of gene targeting techniques has led to new insights into the physiologic function of lymphoid growth factors, their receptors, and associated signal transduction molecules in the formation and function of T and B cells. Mice rendered deficient for the growth factors interleukin-2 or interleukin-4 exhibit impairment in certain immune responses ...
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