Comparison of LPS-stimulated release of cytokines in punch versus transwell tissue culture systems of human gestational membranes [PDF]
, 2010 Background Cytokine signaling within the amnionic, chorionic and decidual extraplacental gestational membranes plays an important role in membrane rupture and the timing of birth.
Loch-Caruso, Rita, Miller, Mark F.
core +4 more sources
Analysis of Lymphocyte Subsets Including Th17 Cells in Alcoholic Liver Disease [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Alcoholic Liver Disease (ALD), which consists of three major diseases: (1) fatty liver, (2) alcoholic hepatitis and (3) cirrhosis, is described to be associated with lymphopenia and an altered ratio of lymphocyte subsets but the reported
BIDYUT BIKASH GOGOI +5 more
doaj +1 more source
Interleukin-18: Perspectives on the Newest Interleukin
Cytokine & Growth Factor Reviews, 1998 Just over two years ago the newest member of the interleukin family of cytokines, IL-18, was molecularly cloned. IL-18 was originally identified as a result of its ability to induce interferon gamma production, however with the advent of its cloning and the production of recombinant protein a number of other biological actions have since been ...
Gillespie, M T, Horwood, N J
openaire +4 more sources
Montmorency cherries reduce the oxidative stress and inflammatory responses to repeated days high-intensity stochastic cycling [PDF]
, 2014 This investigation examined the impact of Montmorency tart cherry concentrate (MC) on physiological indices of oxidative stress, inflammation and muscle damage across 3 days simulated road cycle racing.
Alessio +15 more
core +2 more sources
Interleukin (IL)-1B and IL-1 receptor antagonist gene polymorphisms in children with primary immune thrombocytopenia [PDF]
Clinical and Experimental PediatricsBackground The pathophysiology and susceptibility of children to primary immune thrombocytopenia (ITP) are linked to polymorphisms of the interleukin (IL)-1B and IL-1 receptor (IL-1R) antagonist genes.
Seham Mohamed Ragab +5 more
doaj +1 more source
Interleukin-1 and interleukin-1 antagonism [PDF]
Blood, 1991 The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system. IL-1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a variety of genes and the synthesis of several proteins that, in turn, induce acute and chronic inflammatory changes.
openaire +4 more sources
Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension [PDF]
, 2010 BACKGROUND: Inflammation is a feature of pulmonary arterial hypertension (PAH), and increased circulating levels of cytokines are reported in patients with PAH.
Barker, Lucy +13 more
core +1 more source
miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas
Journal of Extracellular Vesicles, 2020 Exosomes, or small extracellular vesicles (sEVs), serve as intercellular messengers with key roles in normal and pathological processes. Our previous work had demonstrated that Dsg2 expression in squamous cell carcinoma (SCC) cells enhanced both sEV ...
Joseph P. Flemming +12 more
doaj +1 more source
Emerging Roles of Dysregulated MicroRNAs in Myasthenia Gravis
Frontiers in Neuroscience, 2020 Myasthenia gravis (MG) is a rare acquired autoimmune neuromuscular disease. Autoantibodies, cellular immunity, complement, and cytokines are involved in the pathogenesis of MG. It is characterized by the dysfunction of neuromuscular junction transmission
Lin Wang, Lijuan Zhang
doaj +1 more source
Ten interleukins and risk of prostate cancer
Frontiers in Oncology, 2023 BackgroundInterleukins (ILs) have been reported to be related to prostate cancer. The aims of this study were to estimate the levels for several key interleukins in prostate cancer and the causal effects between them.MethodsWe conducted a bi-directional ...
Bing-Hui Li +8 more
doaj +1 more source