Results 31 to 40 of about 697,588 (247)

Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way

Endocrine Connections, 2020
Background: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient i ncreases in cortisol and ACTH secretion occurred.
Ferdinand Roelfsema, Peter Y Liu, Rebecca Yang, Paul Takahashi, Johannes D Veldhuis   +4 more
doaj   +1 more source

Emerging Roles of Dysregulated MicroRNAs in Myasthenia Gravis

Frontiers in Neuroscience, 2020
Myasthenia gravis (MG) is a rare acquired autoimmune neuromuscular disease. Autoantibodies, cellular immunity, complement, and cytokines are involved in the pathogenesis of MG. It is characterized by the dysfunction of neuromuscular junction transmission
Lin Wang, Lijuan Zhang
doaj   +1 more source

Phytocannabinoids Act Synergistically with Non-Steroidal Anti-Inflammatory Drugs Reducing Inflammation in 2D and 3D In Vitro Models

Pharmaceuticals, 2022
Lung inflammation is associated with elevated pro-inflammatory cytokines and chemokines. Treatment with FCBD:std (standard mix of cannabidiol [CBD], cannabigerol [CBG] and tetrahydrocannabivarin [THCV]) leads to a marked reduction in the inflammation of ...
Ajjampura C. Vinayaka, Nurit Shalev, Seegehalli M. Anil, Sudeep Tiwari, Navin Kumar, Eduard Belausov, Karthik Ananth Mani, Guy Mechrez, Hinanit Koltai   +8 more
doaj   +1 more source

Interleukin-18 [PDF]

Journal of Leukocyte Biology, 2003
Abstract Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses. IL-18 is expressed at sites of chronic inflammation, in autoimmune diseases, in a variety of cancers, and in the context of numerous infectious diseases.
Gracie, J.A., Robertson, S.E., McInnes, I.B.   +2 more
openaire   +3 more sources

Type I interferons augment regulatory T cell polarization in concert with ancillary cytokine signals

Frontiers in Transplantation, 2023
In the transplant community, research efforts exploring endogenous alternatives to inducing tolerogenic allo-specific immune responses are much needed.
Siawosh K. Eskandari, Siawosh K. Eskandari, Hazim Allos, Jenelle M. Safadi, Jenelle M. Safadi, Ina Sulkaj, Ina Sulkaj, Jan S. F. Sanders, Paolo Cravedi, Irene M. Ghobrial, Stefan P. Berger, Jamil R. Azzi   +11 more
doaj   +1 more source

Antidesma thwaitesianum Müll. Arg. fruit extract rich in 5-hydroxymethylfurfural exhibits anti-inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophages [PDF]

Journal of HerbMed Pharmacology, 2022
Introduction: Antidesma thwaitesianum Müll. Arg is a tropical fruit, which has been commonly used for healthy food and traditional herbal medicine. This study aimed to investigate the anti-inflammatory effects of A. thwaitesianum fruit extract (AFE) rich
Orapin Insuan, Benchaluk Thongchuai, Supaporn Khamchun, Wimonrut Insuan, Daoyot Daorueang, Plubplung Sansai   +5 more
doaj   +1 more source

Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells

eLife, 2017
The cutaneous wound-healing program is a product of a complex interplay among diverse cell types within the skin. One fundamental process that is mediated by these reciprocal interactions is the mobilization of local stem cell pools to promote tissue ...
Pedro Lee, Rupali Gund, Abhik Dutta, Neha Pincha, Isha Rana, Subhasri Ghosh, Deborah Witherden, Eve Kandyba, Amanda MacLeod, Krzysztof Kobielak, Wendy L Havran, Colin Jamora   +11 more
doaj   +1 more source

Divergent dynamics of inflammatory mediators and multiplex PCRs during airway infection in cystic fibrosis patients and healthy controls: Serial upper airway sampling by nasal lavage

Frontiers in Immunology, 2022
BackgroundIn cystic fibrosis (CF), acute respiratory exacerbations critically enhance pulmonary destruction. Since these mainly occur outside regular appointments, they remain unexplored.
Nina Erdmann, Theresa Schilling, Julia Hentschel, Thomas Lehmann, Philipp von Bismarck, Tobias Ankermann, Franziska Duckstein, Michael Baier, Carlos Zagoya, Jochen G. Mainz, Jochen G. Mainz, Jochen G. Mainz   +11 more
doaj   +1 more source

Bullous pemphigoid—What do we know about the most recent therapies?

Frontiers in Medicine, 2022
IntroductionBullous pemphigoid (BP) is the most common subtype of autoimmune blistering diseases that primarily affects the elderly and is classically defined by the presence of IgG and/or complement C3 against the BP180 and BP230 hemidesmosome proteins.
Faith A. P. Zeng, Dedee F. Murrell, Dedee F. Murrell, Dedee F. Murrell   +3 more
doaj   +1 more source

Optimization of Capture ELISAs for Chicken Cytokines Using Commercially Available Antibodies

Animals, 2022
Cytokines like interferon (IFN)-γ, interleukin (IL)-2, IL-6, IL-10, and IL-12p40 are important biomarkers for characterizing the nature and strength of immune responses.
Paulina Krzysica, Loes Verhoog, Sonja de Vries, Coen Smits, Huub F. J. Savelkoul, Edwin Tijhaar   +5 more
doaj   +1 more source