Results 61 to 70 of about 1,359,664 (362)

Evaluation of inflammatory response in patients undergoing surgical treatment for early and delayed femoral fractures

Archives of Medical Science, 2018
Introduction It has been shown that long bone fractures are correlated with the inflammatory response. In the initial injury, surgical reduction and fixation of fractures induce the immunoinflammatory response.
Mehdi Moghtadaei, Babak Otoukesh, Hamidreza Pazoki-Toroudi, Bahram Boddouhi, Ali Yeganeh   +4 more
doaj   +1 more source

Interleukin-18 [PDF]

Journal of Leukocyte Biology, 2003
Abstract Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses. IL-18 is expressed at sites of chronic inflammation, in autoimmune diseases, in a variety of cancers, and in the context of numerous infectious diseases.
Gracie, J.A., Robertson, S.E., McInnes, I.B.   +2 more
openaire   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

The nutritional roles of zinc for immune system and COVID-19 patients

Frontiers in Nutrition
Zinc (Zn) is a vital micronutrient that strengthens the immune system, aids cellular activities, and treats infectious diseases. A deficiency in Zn can lead to an imbalance in the immune system. This imbalance is particularly evident in severe deficiency
Di Jin, Di Jin, Xinran Wei, Xinran Wei, Yunyi He, Luying Zhong, Huijie Lu, Jiaxin Lan, Yuting Wei, Zheng Liu, Hongbo Liu, Hongbo Liu   +11 more
doaj   +1 more source

Phytocannabinoids Act Synergistically with Non-Steroidal Anti-Inflammatory Drugs Reducing Inflammation in 2D and 3D In Vitro Models

Pharmaceuticals, 2022
Lung inflammation is associated with elevated pro-inflammatory cytokines and chemokines. Treatment with FCBD:std (standard mix of cannabidiol [CBD], cannabigerol [CBG] and tetrahydrocannabivarin [THCV]) leads to a marked reduction in the inflammation of ...
Ajjampura C. Vinayaka, Nurit Shalev, Seegehalli M. Anil, Sudeep Tiwari, Navin Kumar, Eduard Belausov, Karthik Ananth Mani, Guy Mechrez, Hinanit Koltai   +8 more
doaj   +1 more source

Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. [PDF]

, 2009
The innate immune response of airway epithelial cells to airborne allergens initiates the development of T cell responses that are central to allergic inflammation.
Angkasekwinai, Pornpimon, Barranco, Wade T, Corry, David B, Dong, Chen, Goswami, Sangeeta, Greenlee, Kendra J, Kheradmand, Farrah, Polikepahad, Sumanth, Redding, David, Seryshev, Alexander, Shan, Ming, Singh, Bhupinder, Song, Li-zhen, Sur, Sanjiv, Woodruff, Prescott   +14 more
core  

Label-free, single molecule detection of cytokines using optical microcavities [PDF]

, 2007
Interleukin-2 (IL2) is a cytokine that regulates T-cell growth and is used in cancer therapies. By sensitizing a microcavity sensor surface with anti-IL2 and monitoring the resonant frequency, single molecules of IL2 can be ...
Armani, Andrea M., Fraser, Scott E., Vahala, Kerry J.   +2 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Type I interferons augment regulatory T cell polarization in concert with ancillary cytokine signals

Frontiers in Transplantation, 2023
In the transplant community, research efforts exploring endogenous alternatives to inducing tolerogenic allo-specific immune responses are much needed.
Siawosh K. Eskandari, Siawosh K. Eskandari, Hazim Allos, Jenelle M. Safadi, Jenelle M. Safadi, Ina Sulkaj, Ina Sulkaj, Jan S. F. Sanders, Paolo Cravedi, Irene M. Ghobrial, Stefan P. Berger, Jamil R. Azzi   +11 more
doaj   +1 more source

Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]

, 2016
Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht, Changjun Yin, Christian Weber, Coleen A. McNamara, Desheng Hu, Gianluca Grassia, Kulkarni U, Li Peng, Michael Beer, Pasquale Maffia, Prasad Srikakulapu, Rudolf A. Manz, Sai Vineela Bontha, Sarajo K. Mohanta   +13 more
core   +1 more source