Results 61 to 70 of about 1,003,113 (304)
Interleukin-1 and Interleukin-6 in Psoriasis
Journal of Investigative Dermatology, 1990 We report on the levels of expression of IL-1 and IL-6 in skin from psoriasis patients. Different approaches were pursued. Initially, the levels of IL-1 beta and IL-6 were measured in suction blister fluid from lesional and uninvolved skin from psoriasis patients, using a sensitive enzyme-linked immunoabsorbent assay (ELISA) and bio-assay.
Prens, Errol P. +6 more
openaire +2 more sources
The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]
, 2011 Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core +1 more source
Interleukin (IL)-1B and IL-1 receptor antagonist gene polymorphisms in children with primary immune thrombocytopenia [PDF]
Clinical and Experimental PediatricsBackground The pathophysiology and susceptibility of children to primary immune thrombocytopenia (ITP) are linked to polymorphisms of the interleukin (IL)-1B and IL-1 receptor (IL-1R) antagonist genes.
Seham Mohamed Ragab +5 more
doaj +1 more source
Medicina, 2022 Background and Objectives: The elicitation of a host’s immune–inflammatory responses to overcome oral bacterial biofilm challenges is mediated by numerous cytokines. We explored the role of three such cytokines, viz.
Vineet Nair +8 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Begg’s funnel plot evaluated the effect of anti-interleukin-5 on FEV1.
, 2016 Begg’s funnel plot evaluated the effect of anti-interleukin-5 on FEV1.
Ting Liu (45625) +4 more
core +1 more source
The Cytokine Network in Colorectal Cancer: Implications for New Treatment Strategies
Cells, 2022 Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only limited therapeutic options. CRC is not only a genetic disease with several mutations in specific oncogenes and/or tumor suppressor genes such as APC, KRAS, PIC3CA ...
Heidi Braumüller +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Immunoreactivity for interleukin-33 in allergic airway inflammation [PDF]
, 2015 Immunoreactivity for Interleukin-33 in Allergic Airway Inflammation,Cristan Herbert, Melissa M. Bunting, Neil Lambie, Paul S.
Kumar, RK ; https://orcid.org/ +4 more
core +1 more source
Interleukin-6 and tumor necrosis factor-α levels in tear film of Keratoconus patients
Journal of Research in Medical Sciences, 2021 Background: It is hypothesized that increased inflammatory markers in keratoconus (KC) may be one of the causes of corneal damage. The aim of our study was to the measurement of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL)-6 in tear of ...
Alireza Peyman +5 more
doaj +1 more source