Interleukin 1-β concentration during porcine gestation
Ciencia Veterinaria, 2018 IL-1β, a proinflammatory cytokine, is involved in the conceptus implantation, invasion and fetal-maternal immunotolerance. It participates in the development of the trophoblast, communication with the endometrium and it´s necessary for a correct ...
Carolina Lucía Velez +5 more
doaj +1 more source
Polyene Macrolide Antifungal Drugs Trigger Interleukin-1β Secretion by Activating the NLRP3 Inflammasome [PDF]
PLoS ONE, 2011 The use of antimycotic drugs in fungal infections is based on the concept that they suppress fungal growth by a direct killing effect. However, amphotericin and nystatin have been reported to also trigger interleukin-1β (IL-1β) secretion in monocytes but the molecular mechanism is unknown.
Darisipudi, Murthy Narayana +3 more
openaire +5 more sources
Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis. [PDF]
, 2017 BackgroundIntrauterine infection is a primary cause of preterm birth and fetal injury. The pro-inflammatory role of the fetal skin in the setting of intrauterine infection remains poorly characterized. Whether or not inflammation of the fetal skin occurs
Boonkasidecha, Suppawat +4 more
core +3 more sources
Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]
, 2011 Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle +3 more
core +2 more sources
BMC Molecular and Cell Biology, 2022 Background Acetaminophen is commonly recommended for the early analgesia of osteoarthritis. However, the molecular mechanism by which it acts remains unknown.
Jie Gao +4 more
doaj +1 more source
Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]
, 2003 Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Duda, Erno +4 more
core +1 more source
Peran IL-1 β pada Sepsis dan Gangguan Ginjal Akut Bayi Lahir Prematur
Sari Pediatri, 2020 Latar belakang. Interleukin-1β berperan dalam kejadian infeksi/inflamasi pada bayi prematur yang dapat menyebabkan gejala klinis berat. Imaturitas organ dapat menyebabkan kejadian inflamasi yang dapat merangsang pembentukan sitokin, salah satunya ...
Fiva Aprilia Kadi +3 more
doaj +1 more source
Isoflurane induces learning impairment that is mediated by interleukin 1β in rodents. [PDF]
PLoS ONE, 2012 Postoperative cognitive decline is a clinical syndrome. Volatile anesthetics are commonly used during surgery. It is conceivable that volatile anesthetics may contribute to postoperative cognitive decline.
Lin Cao +3 more
doaj +1 more source
Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages [PDF]
Journal of Biological Chemistry, 2015 Metformin, a frontline treatment for type II diabetes mellitus, decreases production of the pro-form of the inflammatory cytokine IL-1β in response to LPS in macrophages. We found that it specifically inhibited pro-IL-1β production, having no effect on TNF-α.
Beth Kelly +3 more
openaire +4 more sources
Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]
, 2015 Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky +6 more
core +2 more sources