Results 201 to 210 of about 1,016,945 (361)

Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs

Advanced Healthcare Materials, EarlyView.
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller, Tamara Nink, Niklas Walter, Erick Angel Lopez Lopez, Hsin‐Fang Chang, Oskar Staufer   +5 more
wiley   +1 more source

Atheroprotective Immunity and Interleukin-10 Linked to Reduced Characteristics of Plaque Stability. [PDF]

JACC Basic Transl Sci
Yu Y, Lin S, Pan Y, He N, Wu Y, Ahmed O, Hedin U, Karlsson MCI, Li N, Gisterå A.   +9 more
europepmc   +1 more source

Effects of the Japanese herbal medicine ?Sho-Saiko-To? (TJ-9) onin vitro interleukin-10 production by peripheral blood mononuclear cells of patients with chronic hepatitis C [PDF]

, 1997
Masayoshi Yamashiki, Akira Nishimura, Hiroyuki Suzuki, S Sakaguchi, Yoshitane Kosaka   +4 more
openalex   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Exercise facilitates post-stroke recovery through mitigation of neuronal hyperexcitability via interleukin-10 signaling. [PDF]

Nat Commun
Schmidt-Pogoda A, Ruck T, Strecker JK, Hoppen M, Fazio L, Vinnenberg L, Maus B, Wachsmuth L, Cerina M, Diederich K, Lichtenberg S, Abberger H, Haertel L, Schafflick D, Meyer Zu Hörste G, Herrmann AM, Hundehege P, Narayanan V, Nelke C, Kruithoff K, Bosbach J, Vicari E, Ramcke T, Beuker C, Hadaschik E, Budde T, Faber C, Wiendl H, Hansen W, Meuth SG, Minnerup J.   +30 more
europepmc   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

Advanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen, Yingjie Fan, Tomas Germanas, Langston Tillman, Jinhong Li, Abigail L. Blenko, Ralph R. Weichselbaum, Wenbin Lin   +7 more
wiley   +1 more source

Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and Tyk2 Inhibitors via Interleukin-10 Antagonism. [PDF]

Arthritis Rheumatol
Giryes S, Wong C, Bridgewood C, Harland M, Altaie A, McDermott N, Abacar K, Rao A, Khan A, McMillan T, Loughenbury P, Dunsmuir R, Borse V, Macleod T, McGonagle D.   +14 more
europepmc   +1 more source

DIFFERENTIAL EFFECTS OF EXOGENOUS INTERLEUKIN-10 ON CARDIAC ALLOGRAFT SURVIVAL1,2

, 1999
Wei Li, Fumin Fu, Lina Lü, Satwant K. Narula, John J. Fung, Angus W. Thomson, Shiguang Qian   +6 more
openalex   +1 more source

Interleukin‐10 is a growth factor for human melanoma cells and down‐regulates HLA class‐I, HLA class‐II and ICAM‐1 molecules [PDF]

, 1997
Feng Yun Yue, Reinhard Dummer, Ralf Geertsen, Günther F.L. Hofbauer, Elisabeth Laine, Silvana Manolio, Günter Burg   +6 more
openalex   +1 more source

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

Advanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi, Junho Byun, Dongyoon Kim, Qiaoyun Li, Dongun Jin, Yeong‐jin Choi, Ho Sang Jung, Jaiwoo Lee, Yu‐Kyoung Oh   +8 more
wiley   +1 more source