Results 71 to 80 of about 1,035,955 (303)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Human Cytomegalovirus Interleukin 10 Homologs: Facing the Immune System

Frontiers in Cellular and Infection Microbiology, 2020
Human Cytomegalovirus (HCMV) can cause a variety of health disorders that can lead to death in immunocompromised individuals and neonates. The HCMV lifecycle comprises both a lytic (productive) and a latent (non-productive) phase.
Emma Poole, Tainan Cerqueira Neves, Martha Trindade Oliveira, John Sinclair, Maria Cristina Carlan da Silva   +4 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

The role of IL10 and IL17 gene polymorphisms in treatment response in children and adolescents with severe asthma [PDF]

Jornal Brasileiro de Pneumologia
Objective: To determine whether polymorphisms of the IL10 and IL17 genes are associated with severe asthma control and bronchodilator reversibility in children and adolescents with severe asthma.
Mariana Isadora Ribeiro Vieira, Mônica Versiani Nunes Pinheiro de Queiroz, Maria Borges Rabelo de Santana, Hatilla dos Santos Silva, Almirane Oliveira, Camila Alexandrina Viana Figueiredo, Eduardo Martín Tarazona Santos, Ryan dos Santos Costa, Laura Maria de Lima Belizário Facury Lasmar   +8 more
doaj   +1 more source

Pathogenetic Characteristics of Anemia in Patients with Solid Tumors [PDF]

Клиническая онкогематология, 2017
Aim. To study the impact iron metabolism disturbances and cytokine levels on the development of anemia in patients with solid tumors. Materials & Methods.
VT Sakhin, ER Madzhanova, EV Kryukov, AV Sotnikov, AV Gordienko, OA Rukavitsyn   +5 more
doaj   +1 more source

Hubungan Peningkatan Interleukin-10 Akibat Infestasi Cacing Usus Nematoda terhadap Spektrum Morbus Hansen [PDF]

, 2015
Morbus Hansen (MH) adalah infeksi kronis yang disebabkan oleh Mycobacterium leprae, yang mengenai saraf perifer, kulit, dan organ lain kecuali susunan saraf pusat. Pertahanan terhadap M.
Lukas, R. (Rika), Rusmawardiana, R. (Rusmawardiana), Thaha, A. (Athuf), Tjekyan, R. M. (R)   +3 more
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Evaluation of Serum Interleukins-6, 8 and 10 Levels as Diagnostic Markers of Neonatal Infection and Possibility of Mortality [PDF]

Iranian Journal of Basic Medical Sciences, 2013
Objective(s): Bacterial infection contributes substantially to neonatal morbidity and mortality. Early diagnosis of neonatal sepsis is difficult because clinical signs are non-specific.
Hassan Boskabadi, Gholamali Maamouri, Jalil Tavakol Afshari, Shahin Mafinejad, Golkoo Hosseini, Hesam Mostafavi-Toroghi, HamidReza saber, majid Ghayour-Mobarhan, Gordon ferns   +8 more
doaj  

Dietary Polyphenols and Periodontitis—A Mini-Review of Literature [PDF]

, 2018
Periodontitis, which is a chronic infection and disease of the periodontium, is a significant global health burden and is linked to other chronic health conditions such as diabetes and cardiovascular diseases.
Basu, Arpita, Ebersole, Jeffrey L., Masek, Emily   +2 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source