Nanoparticle-Mediated Interleukin-12 Cancer Gene Therapy
Journal of Pharmacy & Pharmaceutical Sciences, 2010 Interleukin-12 (Il-12) is a heterodimeric cytokine which has been proved to possess antitumor effects in various animal models via stimulating the immune system.
Crispin Dass +2 more
doaj +1 more source
The effect of exercise on plasma soluble IL-6 receptor concentration: a dichotomous response [PDF]
, 2010 The aim of this article is to review current literature on the response of soluble interleukin-6 receptor to exercise and identify a potential role for sIL-6R in skeletal muscle function.
Cockburn, Emma +4 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
Soluble ST2 levels and left ventricular structure and function in patients with metabolic syndrome [PDF]
, 2016 Background: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family.
Beunza, Maite +14 more
core +1 more source
Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration
Arthritis Care &Research, EarlyView.Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget +7 more
wiley +1 more source
Expression of interleukin 2 receptors on activated human B cells. [PDF]
, 1984 Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
Bongiovanni, KF +8 more
core
Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. [PDF]
, 1990 BALB/c mice infected with Leishmania major develop fatal, progressive disease, despite an immune response characterized by expansion of CD4+ T cells in the draining lymph nodes.
Dawkins, RS +5 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart +14 more
wiley +1 more source
Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10. [PDF]
, 1996 The mechanism by which the mammalian mother accepts the implanting fetus as an allograft remains unexplained, but is likely to be the result of a combination of factors.
Abrams, JS +5 more
core +1 more source
Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study [PDF]
, 2015 Objectives The interleukin-6 receptor (IL-6R) blocker tocilizumab (TCZ) reduces inflammatory disease activity in rheumatoid arthritis (RA) but elevates lipid concentrations in some patients.
Bathon, Joan M. +10 more
core +1 more source