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Interleukin 13 Promotes Maturation and Proliferation in Metaplastic GastroidsSummary [PDF]

Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: Type 2 innate lymphoid cells (ILC2s) and interleukin-13 (IL-13) promote the onset of spasmolytic polypeptide-expressing metaplasia (SPEM) cells. However, little is known about molecular effects of IL-13 in SPEM cells. We now sought
Ela W. Contreras-Panta, Su-Hyung Lee, Yoonkyung Won, Allison E. Norlander, Alan J. Simmons, R. Stokes Peebles, Jr., Ken S. Lau, Eunyoung Choi, James R. Goldenring   +8 more
doaj   +2 more sources

Interleukin-13 [PDF]

Definitions, 2020
openaire   +2 more sources

Interleukin 13 Measurement [PDF]

Definitions, 2020
openaire   +2 more sources

Recombinant Interleukin-13 [PDF]

Definitions, 2020
openaire   +2 more sources

Interleukin-13 (IL-13) Pathway [PDF]

Science's STKE, 2005
Interleukin-13 (IL-13), like IL-4, is a cytokine produced by T H 2 type helper T cells in response to signaling through the T cell antigen receptor and by mast cells and basophils upon cross-linkage of the high-affinity receptor for immunoglobulin E (IgE). It is also produced by activated eosinophils.
Ann, Kelly-Welch, Erica M, Hanson, Achsah D, Keegan   +2 more
openaire   +2 more sources

Interleukin 13 receptor alpha 2 (IL13Rα2): Expression, signaling pathways and therapeutic applications in cancer.

Biochimica et biophysica acta. Reviews on cancer, 2022
Interleukin 13 receptor alpha 2 (IL13Rα2) is increasingly recognized as a relevant player in cancer invasion and metastasis Despite being initially considered a decoy receptor for dampening the levels of interleukin 13 (IL-13) in diverse inflammatory ...
M. Jaén, Ángela Martín-Regalado, Rubén A. Bartolomé, Javier Robles, J. Casal   +4 more
semanticscholar   +1 more source

An Interleukin-4 and Interleukin-13 Induced Atopic Dermatitis Human Skin Equivalent Model by a Skin-On-A-Chip

International Journal of Molecular Sciences, 2022
Currently, the mechanism of progression of atopic dermatitis (AD) is not well understood because there is no physiologically appropriate disease model in terms of disease complexity and multifactoriality. Type 2 inflammation, mediated by interleukin (IL)-
Kyunghee Kim, Hyeju Kim, G. Sung
semanticscholar   +1 more source

Cytokines Involved in the Pathogenesis of SSc and Problems in the Development of Anti-Cytokine Therapy

Cells, 2021
Systemic sclerosis (SSc) is a connective tissue disease of unknown etiology. SSc causes damage to the skin and various organs including the lungs, heart, and digestive tract, but the extent of the damage varies from patient to patient.
Yoshihito Shima
doaj   +1 more source

Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for people with asthma.

Cochrane Database of Systematic Reviews, 2021
BACKGROUND Targeting the immunoglobulin E pathway and the interleukin-5 pathway with specific monoclonal antibodies directed against the cytokines or their receptors is effective in patients with severe asthma.
Andrew Gallagher, Michaela Edwards, Parameswaran Nair, Stewart Drew, A. Vyas, Rashmi Sharma, P. Marsden, Ran Wang, David J W Evans   +8 more
semanticscholar   +1 more source

Butyrate and propionate restore interleukin 13‐compromised esophageal epithelial barrier function

Allergy. European Journal of Allergy and Clinical Immunology, 2021
Eosinophilic esophagitis (EoE) is a food allergen driven disease that is accompanied by interleukin (IL) 13 overexpression and esophageal barrier dysfunction allowing transepithelial food allergen permeation.
M. Kleuskens, Maria-Louise Haasnoot, Bart M Herpers, M. V. van Ampting, A. Bredenoord, J. Garssen, F. Redegeld, B. Van Esch   +7 more
semanticscholar   +1 more source