Results 51 to 60 of about 4,629,468 (340)

In vitro initial immune response against Leishmania amazonensis infection is characterized by an increased production of IL-10 and IL-13

Brazilian Journal of Infectious Diseases
The initial encounter of Leishmania with its host's immune system is important in the outcome of infection. Previous studies have shown that PBMCs from healthy volunteers (HV) exposed to Leishmania differ in IFN-γ production.
Zirlane Castelo B Coêlho, Maria Jania Teixeira, Erika Freitas Mota, Mércia Sindeaux Frutuoso, João Santana da Silva, Aldina Barral, Manoel Barral-Netto, Margarida Maria L Pompeu   +7 more
doaj   +1 more source

Lack of association between interleukin 13, interleukin 4 receptor alpha, andMS4A2 gene polymorphisms and asthma in adult Saudis

Journal of Nature and Science of Medicine, 2020
Objectives: Several genes, including interleukin-13 (IL13), MS4A2, and IL 4 receptor alpha (IL4Rα), have been shown to associate with the inflammatory process in asthma.
Eman A Al Abdulsalam, Mohamed S Al-Hajjaj, Mohammad S Alanazi, Arjumand S Warsy   +3 more
doaj   +1 more source

Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. [PDF]

, 2016
Group 2 innate lymphoid cells (ILC2s) and type 2 helper T cells (Th2 cells) are the primary source of interleukin 5 (IL-5) and IL-13 during type 2 (allergic) inflammation in the lung.
Austen, K Frank, Barrett, Nora A, Kanaoka, Yoshihide, Locksley, Richard M, O'Leary, Claire E, von Moltke, Jakob   +5 more
core   +1 more source

The Presence of Interleukin-13 at Pancreatic ADM/PanIN Lesions Alters Macrophage Populations and Mediates Pancreatic Tumorigenesis.

Cell Reports, 2017
The contributions of the innate immune system to the development of pancreatic cancer are still ill defined. Inflammatory macrophages can initiate metaplasia of pancreatic acinar cells to a duct-like phenotype (acinar-to-ductal metaplasia [ADM]), which ...
Geou-Yarh Liou, Ligia I. Bastea, Alicia K Fleming, Heike R. Döppler, B. Edenfield, D. Dawson, Lizhi Zhang, N. Bardeesy, P. Storz   +8 more
semanticscholar   +1 more source

Th17 Lymphocytes in Respiratory Syncytial Virus Infection

Viruses, 2013
Infection by respiratory syncytial virus (RSV) affects approximately 33 million infants annually worldwide and is a major cause of hospitalizations. Helper T lymphocytes (Th) play a central role in the immune response during such infections.
Rizgar A. Mageed, Ali S. Jawad, Mohammed Al-Bogami, Nasra Al-Adhoubi, Jonas Bystrom   +4 more
doaj   +1 more source

CD4(+)IL-13(+) cells in peripheral blood well correlates with the severity of atopic dermatitis in children [PDF]

, 2005
In atopic dermatitis (AD) a Th1/Th2 imbalance has been reported, and interleukin (IL)-13 seems to play a pivotal role in the inflammatory network. We tried to assess the correlation between the immunological marker CD4(+)IL-13(+) and the clinical phase ...
CITARRELLA, Roberto, GIORDANO, Carla, LA GRUTTA, Stefania, MATTINA, Antonina, Pajno, G., PASSALACQUA, Girolamo, PIZZOLANTI, Giuseppe, RICHIUSA, Pierina   +7 more
core   +1 more source

The gene encoding interleukin-13: a susceptibility locus for asthma and related traits

Respiratory Research, 2000
Asthma is a complex inflammatory disorder controlled by both genetic and environmental influences. Multiple genetic analyses have identified the T helper type 2 (Th2) cytokine gene cluster on chromosome 5q as a susceptibility locus for asthma.
Wills-Karp Marsha
doaj   +1 more source

Cilia‐Mediated Insulin/Akt and ST2/JNK Signaling Pathways Regulate the Recovery of Muscle Injury

Advanced Science, 2023
Following injury, skeletal muscle regenerates but fatty tissue accumulation is seen in aged muscle or muscular dystrophies. Fibro/adipogenic progenitors (FAPs) are key players in these events; however, the effect of primary cilia on FAPs remains unclear.
Daishi Yamakawa, Junya Tsuboi, Kousuke Kasahara, Chise Matsuda, Yuhei Nishimura, Tatsuya Kodama, Naoyuki Katayama, Masatoshi Watanabe, Masaki Inagaki   +8 more
doaj   +1 more source

Interleukin-13 Genetic Variants, Household Carpet Use and Childhood Asthma [PDF]

, 2013
10.1371/journal.pone.0051970PLoS ...
Chew, F.T., Chiang, B.-L., Kuo, N.-W., Lee, Y.L., Su, M.-W., Tsai, C.-H., Tung, K.-Y.   +6 more
core   +3 more sources

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source