Results 61 to 70 of about 5,344,313 (294)

Th2 Cytokines Increase the Expression of Fibroblast Growth Factor 21 in the Liver

Cells, 2021
Interleukin-4 (IL-4) and IL-13 are the major T helper 2 (Th2) cytokines, and they are involved in the regulation of metabolism in the adipose tissue. The liver contains diverse innate and adaptive immune cells, but it remains to be determined whether Th2
Seul-Gi Kang, Seong-Eun Lee, Min-Jeong Choi, Joon-Young Chang, Jung-Tae Kim, Ben-Yuan Zhang, Yea-Eun Kang, Ju-Hee Lee, Hyon-Seung Yi, Minho Shong   +9 more
doaj   +1 more source

Efeito inibitório da interleucina-4 e interleucina-13 sobre a hiperalgesia inflamatória [PDF]

, 2000
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.O presente estudo utilizou um modelo de hiperalgesia mecânica (teste de Randall-Selitto modificado) para investigar os efeitos da interleucina(IL)-4 e IL-13 ...
Veiga, Fabiane Hiratsuka
core  

Prevention of arthritis by interleukin 10-producing B cells [PDF]

, 2003
In this study we have shown that activation of arthritogenic splenocytes with antigen and agonistic anti-CD40 gives raise to a B cell population that produce high levels of interleukin (IL)-10 and low levels of interferon (IFN)-{gamma}. Transfer of these
Mauri, C., Mushtaq, N., Marco Londei, Claudia Mauri, Naseem Mushtaq, Gray, D., Londei, M., David Gray   +7 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem, Herrmann, Eva, Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Rudloff, Ina, Bernd Kronenberger, Waidmann, Oliver, Albrecht Piiper, Pfeilschifter, Josef (Prof. Dr.), Piiper, Albrecht, Heiko Mühl, Filmann, Natalie, Ina Rudloff, Malte Bachmann, Eva Herrmann, Josef Pfeilschifter, Lisa Kapper, Bachmann, Malte, Brunner, Friederike, Kapper, Lisa, Mühl, Heiko, Natalie Filmann, Zeuzem, Stefan   +23 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Effect of yeast probiotic Saccharomyces boulardii cell wall extract on Aspergillus fumigatus allergenicity in A549 cells [PDF]

Current Medical Mycology
Background and Purpose: Interest in probiotic use for respiratory allergies has increased. In this regard, the present study aimed to evaluate the effect of cell wall extractof Saccharomyces boulardii on Aspergillus fumigatus as an allergenic fungus and ...
Donya Nikaein, Haleh Malekmadani, Babak Beikzadeh, Reza Mardanpour, Alireza Khosravi, Seyed Mohammad Moghadami   +5 more
doaj   +1 more source

Preeclampsia Susceptibility Assessment Based on Deep Learning Modeling and Single Nucleotide Polymorphism Analysis

Biomedicines, 2023
The early diagnosis of preeclampsia, a key outlook in improving pregnancy outcomes, still remains elusive. The present study aimed to examine the interleukin-13 and interleukin-4 pathway potential in the early detection of preeclampsia as well as the ...
Aida Saadaty, Sara Parhoudeh, Khalil Khashei Varnamkhasti, Mehdi Moghanibashi, Sirous Naeimi   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Association between the Polymorphisms of IL-4 Gene Promoter (-590C>T), IL-13 Coding Region (R130Q) and IL-16 Gene Promoter (-295T>C) and Allergic Asthma

Iranian Journal of Allergy, Asthma and Immunology, 2007
Allergic asthma is a multifactorial disease, influenced by genetic and environmental factors. Recent family-based studies have revealed evidence for linkage of human chromosomes 5q31-33, 12q15-24, 11q13 and 15q23.6 as regions likely to contain genes ...
Sara Hosseini-Farahabadi, Jalil Tavakkol-Afshari, Houshang Rafatpanah, Reza Farid-Hosseini, Mohammad Khaje Daluei   +4 more
doaj