Results 51 to 60 of about 5,344,313 (294)
Effects of interleukin 4 on monocyte functions: comparison to interleukin 13 [PDF]
Research in Immunology, 1993 Contains fulltext : 27153.PDF (Publisher’s version ) (Open Access)
Waal Malefijt, R. de +2 more
openaire +3 more sources
, 2019 To use human limbal explants as an alternative source for generating conjunctival epithelium and to determine the effect of interleukin-13 (IL-13) on goblet cell number, mucin expression, and stemness. Human limbal explants prepared from 17 corneoscleral
Pavlina Skalicka (3929549) +4 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Trends in Pharmaceutical Sciences, 2016 Brucella is an intracellular Gram-negative bacterium. Previous reports showed that gene polymorphisms of cytokines can affect resistance or susceptibility to Brucella infection.
Sayed-Jalal-Aladin Ashraf-Mansuri +5 more
doaj
Role of IL-4 and IL-13 in Cutaneous T Cell Lymphoma
LifeThe interleukins IL-4 and IL-13 are increasingly recognized contributors to the pathogenesis of cutaneous T cell lymphomas (CTCLs), and their role in disease-associated pruritus is accepted.
Roberto Mazzetto +5 more
doaj +1 more source
The gene encoding interleukin-13: a susceptibility locus for asthma and related traits
Respiratory Research, 2000 Asthma is a complex inflammatory disorder controlled by both genetic and environmental influences. Multiple genetic analyses have identified the T helper type 2 (Th2) cytokine gene cluster on chromosome 5q as a susceptibility locus for asthma.
Wills-Karp Marsha
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Frontiers in ImmunologyBackgroundInterleukins IL-4, Il-5, IL-10, IL-13 and IL-33 play an important role in atopic dermatitis patients. The aim of our study is to address several knowledge gaps in the understanding of interleukin dynamics in atopic dermatitis patients and the ...
Jarmila Čelakovská +3 more
doaj +1 more source
Interleukin-25 Mediated Induction of Angiogenin-4 Is Interleukin-13 Dependent. [PDF]
PLoS ONE, 2016 The intestinal surface is directly exposed to both commensal microorganisms as well as pathogens with a single layer of epithelium separating luminal microorganisms from internal tissues.
Zannatun Noor +3 more
doaj +1 more source