Results 201 to 210 of about 4,008,604 (402)

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Nature Immunology, 2005
Heon Park, Zhaoxia Li, Xuexian O. Yang, S. Chang, R. Nurieva, Yi-hong Wang, Ying Wang, L. Hood, Zhou Zhu, Qiang Tian, C. Dong   +10 more
semanticscholar   +1 more source

Nanozymes for Treating Ocular Diseases

Advanced Healthcare Materials, Volume 14, Issue 8, March 25, 2025.
Nanozymes, with their nanoscale size and enzyme‐like activities, can reduce inflammation and oxidative stress associated with various ocular diseases. Recent research explores their integration with soft materials, nanoparticles, and drug delivery systems, promising enhanced therapeutic outcomes.
Ka‐Ying Wong, Man‐Sau Wong, Juewen Liu   +2 more
wiley   +1 more source

Evaluation of the T helper 17 cell specific genes and the innate lymphoid cells counts in the peripheral blood of patients with the common variable immunodeficiency

Journal of Research in Medical Sciences, 2014
Background: Common variable immunodeficiency (CVID) is characterized by a deficiency in the immune system with a heterogeneous collection of disorders resulting in antibody deficiency and recurrent infections.
Mazdak Ganjalikhani-Hakemi, Reza Yazdani, Roya Sherkat, Vida Homayouni, Mohsen Masjedi, Mohsen Hosseini   +5 more
doaj  

Interleukin-17 promotes angiogenesis and tumor growth [PDF]

, 2002
M. Numasaki
openalex   +1 more source

A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper presents a microphysiological system containing an array of individually addressable living corneal tissues constructed using primary human cells. The bioengineered eye model can simulate acute exposure of the human cornea to different types of environmental toxicants and provides a novel platform for visualization and quantitative ...
Se‐jeong Kim, Ning Guo, Zong Yao Tan, Xing Gao, Pouria Fattahi, Haijiao Liu, Jeehan Chang, Mousa Younesi, Selice Jung, Yewhan Chung, Minkyung Song, Michelle Jung, Dan Dongeun Huh   +12 more
wiley   +1 more source

Ginsenoside F2 attenuates chronic-binge ethanol-induced liver injury by increasing regulatory T cells and decreasing Th17 cells

Journal of Ginseng Research, 2020
Background: Recently, beneficial roles of ginsenoside F2 (GF2), a minor constituent of Panax ginseng, have been demonstrated in diverse inflammatory diseases. However, its roles in alcoholic liver inflammation and injury have not been clearly understood.
Myung-Ho Kim, Hee-Hoon Kim, Jong-Min Jeong, Young-Ri Shim, Jun-Hee Lee, Ye Eun Kim, Tom Ryu, Keungmo Yang, Kyu-Rae Kim, Byeong-Min Jeon, Sun Chang Kim, Jae-Kwang Jung, Jae-Kap Choi, Young-Sun Lee, Jin-Seok Byun, Won-Il Jeong   +15 more
doaj  

Soluble and Transmembrane Isoforms of Novel Interleukin-17 Receptor-like Protein by RNA Splicing and Expression in Prostate Cancer [PDF]

, 2002
Dominik R. Haudenschild, Timothy A. Moseley, Larry Rose, A. Hari Reddi   +3 more
openalex   +1 more source

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden, Raquel Alonso‐Román, Johannes Stallhofer, Mark S. Gresnigt, Bernhard Hube, Alexander S. Mosig   +5 more
wiley   +1 more source

Machine learning discoveries of ASCL2-X synergy in ETC-1922159 treated colorectal cancer cells [PDF]

arXiv
Achaete-scute complex homolog 2 (ASCL2) codes a part of the basic helix-loop-helix (BHLH) transcription factor family. WNTs have been found to directly affect the stemness of the tumor cells via regulation of ASCL2. Switching off the ASCL2 literally blocks the stemness process of the tumor cells and vice versa.
arxiv  

Immune‐Infiltrated Cancer Spheroid Model with Vascular Recirculation Reveals Temporally Dependent and Tissue‐Specific Macrophage Recruitment

Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.
The migration and infiltration of circulating monocytes into cancer spheroids are shown using a pumpless recirculating platform. This method allows for the continuous circulation of immune cells, which is essential for observing the long‐term dynamic behavior of immune cells within cancer environments.
Feng Zhang, Kimia Asadi Jozani, Anushree Chakravarty, Dawn Lin, Andrew Hollinger, Shravanthi Rajasekar, Boyang Zhang   +6 more
wiley   +1 more source