Estimating Optimal Dynamic Treatment Regimes Using Irregularly Observed Data: A Target Trial Emulation and Bayesian Joint Modeling Approach [PDF]
arXivAn optimal dynamic treatment regime (DTR) is a sequence of decision rules aimed at providing the best course of treatments individualized to patients. While conventional DTR estimation uses longitudinal data, such data can also be irregular, where patient-level variables can affect visit times, treatment assignments and outcomes. In this work, we first
arxiv
Interleukin‐17 in rheumatoid arthritis: If T cells were to contribute to inflammation and destruction through synergy [PDF]
, 2003 Pierre Miossec
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Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.This study optimizes sterilization methods for bioprinted 3D corneal stroma patches made from cornea‐derived decellularized extracellular matrix (Co‐dECM) hydrogels and human keratocytes. It demonstrates the superiority of electron beam sterilization in preserving the mechanical, biochemical, and immunomodulatory properties of hydrogels, ensuring ...
Jungbin Yoon +4 more
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Inhibition of Interleukin-17 Prevents the Development of Arthritis in Vaccinated Mice Challenged withBorrelia burgdorferi [PDF]
, 2003 Matthew A. Burchill +6 more
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Th17 Cell-Associated Response to Borrelia Burgdorferi Outer Surface Protein A [PDF]
, 2014 Arthritis is a common symptom of Lyme disease, a debilitating condition resulting from infection with Borrelia burgdorferi. A protein found on the surface of B.
Johnson, Megan Elizabeth
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Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
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T-cell-derived Interleukin-17 Regulates the Level and Stability of Cyclooxygenase-2 (COX-2) mRNA through Restricted Activation of the p38 Mitogen-activated Protein Kinase Cascade [PDF]
, 2003 Wissam H. Faour +3 more
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Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models
Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario +2 more
wiley +1 more source
Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6. [PDF]
, 2003 Astrid Kehlen +3 more
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