Results 301 to 310 of about 4,008,604 (402)

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Wenxiang Meng and colleagues delve into the molecular mechanisms underlying curcumin's modulation of RNA post‐transcriptional N (6)‐methyladenosine (m6A) modification. It is found that curcumin interacts with the Z1‐type protein tyrosine phosphatase receptor (PTPRZ1), maintaining its enzymatic activity and thus regulating the phosphorylation of the m6A‐
Ninan Zhang, Ruifan Lin, Wenya Gao, Honglin Xu, Yuejia Li, Xiahe Huang, Yingchun Wang, Xianghong Jing, Wenxiang Meng, Qi Xie   +9 more
wiley   +1 more source

Hypoxia Combined With Interleukin-17 Regulates Hypoxia-Inducible Factor-1α/Endothelial Nitric Oxide Synthase Expression in Pulmonary Artery Endothelial Cells. [PDF]

J Cell Mol Med
Sun S, Mao J, Ding Y, Liu L, Gong J, Yang S, Li J, Kuang T, Miao R, Yang Y.   +9 more
europepmc   +1 more source

T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17

, 2006
Manu Rangachari, Nora Mauermann, René R. Marty, Stephan Dirnhofer, Michael Kurrer, Vukoslav Komnenovic, Josef Penninger, Urs Eriksson   +7 more
openalex   +1 more source

Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction [PDF]

, 2008
Hideki Ogura, Masaaki Murakami, Yuko Okuyama, Mineko Tsuruoka, Chika Kitabayashi, Minoru Kanamoto, Mika Nishihara, Yoichiro Iwakura, Toshio Hirano   +8 more
openalex   +1 more source

Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis

Advanced Science, Volume 12, Issue 18, May 15, 2025.
An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou, Li Li, Peidi Ren, Ting‐Ting Zhou, Fan He, Jialing Chen, Huimin Cai, Xiumin Han, Yao‐Dong Wu, Jiandong Li, Xiu‐Rong Li, Qiming Tan, Wenhui Li, Qi Chen, Nian‐Zhang Zhang, Xiuju He, Wei‐Gang Chen, Yanping Zhao, Jiwen Sun, Qian Zhang, Yan‐Tao Wu, Yingan Liang, Jie You, Guohai Hu, Xue‐Qi Tian, Sha Liao, Bao‐Quan Fu, Ao Chen, Xue‐Peng Cai, Huanming Yang, Jian Wang, Xin Jin, Xun Xu, Wan‐Zhong Jia, Junhua Li, Hong‐Bin Yan   +35 more
wiley   +1 more source

Diagnostic value of serum vascular endothelial growth factor and interleukin-17 in primary hepatocellular carcinoma. [PDF]

World J Gastrointest Surg
Tian Q, Zeng H, Lu QQ, Xie HY, Li Y.
europepmc   +1 more source

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

Advanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang, Runhua Zhou, Chengchao Xu, Lingyun Dai, Rui Hou, Liuhai Zheng, Chunjin Fu, Guangwei Shi, Jingwei Wang, Yang Li, Jinpeng Cen, Xiaolong Xu, Le Yu, Yilei Li, Jigang Wang, Qingfeng Du, Zhijie Li   +16 more
wiley   +1 more source

Regulation of gut commensal flora attenuates osteoarthritis through interleukin 17

Journal of Orthopaedic Translation, 2016
Dongsheng Yu, Jun Dai, Hongwei Ouyang, Li Dak Sum, Yip Yio Chin   +4 more
doaj   +1 more source

Meta-analysis of the association between interleukin-17 and ischemic cardiovascular disease. [PDF]

BMC Cardiovasc Disord
Miao Y, Yan T, Liu J, Zhang C, Yan J, Xu L, Zhang N, Zhang X.   +7 more
europepmc   +1 more source

Oestrogen modulates experimental autoimmune encephalomyelitis and interleukin‐17 production via programmed death 1 [PDF]

, 2008
Chunhe Wang, Babak Dehghani, Yuexin Li, Laurie J. Kaler, Arthur A. Vandenbark, Halina Offner   +5 more
openalex   +1 more source