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Interleukin 17 is a chief orchestrator of immunity

Nature Immunology, 2017
Increased understanding of the biology of interleukin 17 (IL-17) has revealed that this cytokine is a central player in immunity at the sites most exposed to microorganisms. Although it has been strongly associated with immunopathology, IL-17 also has an important role in host defense.
M. Veldhoen
semanticscholar   +4 more sources

Interleukin-17

Encyclopedia of Molecular Pharmacology, 2021
C. Huppertz
semanticscholar   +2 more sources

Interleukin-17 in Liver Disease Pathogenesis

Seminars in liver disease (Print), 2021
Interleukin 17A (IL-17A)-producing T helper 17 (Th17) cells were identified as a subset of T helper cells that play a critical role in host defense against bacterial and fungal pathogens.
Na Li   +3 more
semanticscholar   +1 more source

Measurement of Interleukin 17 [PDF]

open access: possibleCurrent Protocols in Immunology, 2001
AbstractThis unit describes two procedures for measurement of interleukin‐17 (IL‐17). IL‐17 is a pleiotropic proinflammatory cytokine that binds to its ubiquitously expressed receptor, IL‐17R, resulting in the induction of several other cytokines including IL‐6 and IL‐8.
Jeffrey I. Cohen, Andriani C. Patera
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Interleukin-17

International Reviews of Immunology, 1998
The particular interest of IL-17, a homodimeric cytokine of about 32 kDa, is the strict requirement for an activation signal to induce its expression from a rather restricted set of cells, human memory T cells or mouse alpha beta TCR+CD4-CD8- thymocytes.
F, Fossiez   +5 more
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Measurement of Interleukin‐17

Current Protocols in Immunology, 2007
AbstractUpon antigenic stimulation, naive CD4+ T cells undergo proliferation and differentiate into cytokine‐producing T helper (TH) effector cells. TH1 cells secrete effector cytokine IFN‐γ and regulate cell‐mediated immunity, whereas TH2 cells produce IL‐4, IL‐5, and IL‐13 cytokines, and mediate immunity against extracellular pathogens and allergic ...
Chen Dong, Bhanu P. Pappu
openaire   +3 more sources

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