Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah +8 more
wiley +1 more source
Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow +40 more
core +1 more source
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij +11 more
wiley +1 more source
Caspase-1 activation of interleukin-1β (IL-1β) and IL-18 is dispensable for induction of experimental cerebral malaria. [PDF]
Malaria infection is initiated by sporozoite invasion of hepatocytes and asexual reproduction of liver stages, processes that are regarded to be "clinically and diagnostically silent." Merozoites, which egress from hepatocytes, infect erythrocytes in ...
Matuschewski, K. +9 more
core +1 more source
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato +27 more
wiley +1 more source
Interleukin-18 gene 105A/C genetic polymorphism is associated with the susceptibility of Kawasaki disease. [PDF]
[[abstract]]"Interleukin-18 (IL-18)-656T/G, -607A/C, and -137C/G promoter polymorphisms had been reported associated with Kawasaki disease (KD). An IL-18 genetic A/C polymorphism at coding position 105 (rs549908) has been linked with asthma, rheumatoid ...
;Chen, SY;萬磊;Wan, Lei;Huang, YC;Sheu, JJ;Lan, YC;Lai, CH;Lin, CW;Chang, JS;Tsai, Y;Liu, SP;Lin, YJ;Tsai, FJ
core
Clinical Value of Serum Interleukin-18 in Neonatal Sepsis Diagnosis and Mortality Prediction
Xiaojuan Li, Tiewei Li, Geng Dong, Yulei Wei, Zhe Xu, Junmei Yang Zhengzhou Key Laboratory of Children’s Infection and Immunity, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Zhengzhou ...
Li X, Li T, Dong G, Wei Y, Xu Z, Yang J
doaj
From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss +9 more
wiley +1 more source
Interleukin-18 gene 105A/C genetic polymorphism is associated with the susceptibility of Kawasaki disease [PDF]
[[abstract]]Interleukin-18 (IL-18)-656T/G, -607A/C, and -137C/G promoter polymorphisms had been reported associated with Kawasaki disease (KD). An IL-18 genetic A/C polymorphism at coding position 105 (rs549908) has been linked with asthma, rheumatoid ...
Chen SY;Lei Wan;Huang YC;Sheu JJ;Lan YC;Lai CH;Lin CW;Chang JS;Tsai Y;Liu SP;Lin YJ;Tsai FJ
core +1 more source
New strategies to control inflammatory synovitis: interleukin 15 and beyond [PDF]
No abstract ...
Harnett, W. +4 more
core +1 more source

