Results 91 to 100 of about 63,552,420 (203)

Inflammatory Cytokine Genetics and Coronary Artery Disease: Pathogenetic and Protective Analysis of IL-18 (−607 C/A, −137 G/C) and IL-8 (+781 C/T) Gene Variations

Current Issues in Molecular Biology
Chronic inflammation mediated by cytokines is central to the pathogenesis of coronary artery disease (CAD). This exploratory study aimed to investigate potential associations between functional gene variations of the cytokines interleukin 18 (IL-18) and ...
Arzu Ay, Nevra Alkanli, Gokay Taylan, Esra Ergin   +3 more
doaj   +1 more source

Interleukin-6 and tumor necrosis factor-α are not increased in patients with type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness

, 2004
Interleukin-6 and tumor necrosis factor-α are not increased in patients with type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin ...
MA Febbraio (9644273), Clinton Bruce (13064589), AL Carey (14534870), M Sacchetti (13701022), MJ Anderson (8365899), B Saltin (13701028), JA Hawley (9629840), DB Olsen (15871553)   +7 more
core  

Co-delivery of IL-12/IL-15/IL-18 engineered DC vaccines with anti-IL-10R and nanoconjugated methotrexate in melanoma

Frontiers in Immunology
BackgroundIn an immunosuppressive microenvironment created by melanoma cells, interleukin (IL)-10 can promote tumor growth and impair the function of antigen-presenting cells, particularly dendritic cells.
Katarzyna Węgierek-Ciura, Agnieszka Szczygieł, Anna Rudawska, Jagoda Mierzejewska, Joanna Rossowska, Bożena Szermer-Olearnik, Marta Świtalska, Tomasz M Goszczyński, Elżbieta Pajtasz-Piasecka   +8 more
doaj   +1 more source

Expression and prognostic value of serum Nrf2, NLRP3 and IL-18 in elderly patients with sepsis complicated with acute kidney injury

Guoji laonian yixue zazhi
[Objective] To analyze the expression of serum nuclear factor E2 related factor 2 (Nrf2), NOD-like receptor protein 3 (NLRP3) inflammasomes and interleukin-18 (IL-18) in elderly patients with sepsis complicated with acute kidney injury (AKI) and their ...
Zhao Liang, Guo Wenjuan, Wang Huangsuo, Su Huimei   +3 more
doaj   +1 more source

Association of Interleukin-18 gene polymorphism -137G/C with Allergic rhinitis

مجله دانشگاه علوم پزشکی گرگان, 2015
Background and Objective: The interleukin-18 (IL-18) gene on chromosome 11 has been suggested as a susceptibility factor for allergies. It is a member of the IL-1 family that was originally described as interferon (IFN-γ)–inducing factor.
Ramazi Sh, Khazraei HR, Motovalibashi M, Iziy E, Hashemzade Chaleshtori M, Abolhassani M   +5 more
doaj  

Begg’s funnel plot evaluated the effect of anti-interleukin-5 on FEV₁.

, 2016
Begg’s funnel plot evaluated the effect of anti-interleukin-5 on FEV1.
Ting Liu (45625), Fa-Ping Wang (3358667), Hui Mao (115181), Zhu Lan (3358673), Su-Yun Li (3358670)   +4 more
core   +1 more source

Effects of combined cyclosporin and azithromycin treatment on human mononuclear cells under lipopolysaccharide challenge

Frontiers in Oral Health
ObjectiveTo evaluate the combined effects of azithromycin and varying concentrations of cyclosporin on peripheral blood mononuclear cells (PBMCs) under lipopolysaccharide (LPS) stimulation.Materials and methodsPBMCs were isolated from four healthy donors
Norah Alotaibi, Aminah Alesawy, Marwa Alalshaikh, Faisal E. Aljofi, Nada Aldossary, Nada Alzahrani, Omar Omar, Marwa Madi   +7 more
doaj   +1 more source

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.

, 2007
Interleukin-6 (IL-6) is a key inflammatory cytokine, signalling to most tissues by binding to a soluble IL-6 receptor (sIL-6r), making a complex with gp130.
A Murray, Henley, W, Bandinelli, S, S Rafiq, Rafiq, S, Weedon, MN, Guralnik, JM, Hurst, A, A-M Corsi, Ferrucci, L, K Stevens, S Bandinelli, M N Weedon, Corsi, A-M, L Ferrucci, Murray, A, D Melzer, W Henley, T M Frayling, J M Guralnik, A Hurst, Stevens, K, Melzer, D, Frayling, TM   +23 more
core   +1 more source

Studying the Effect of 12 Weeks of Resistance Training with Sumac Supplementation on Inflammatory and Apoptotic Indices in Male Alzheimer\'s Mice [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Alzheimer's disease represents the most prevalent form of dementia, characterized by a gradual decline in memory function. This study aimed to examine the impact of 12 weeks of resistance training combined with sumac supplementation on ...
Akbar Yeganeh Hashemi, Abbas Sarmi, Mohammad Reza Afarinesh   +2 more
doaj  

The role of interleukin 18 and interleukin 18 binding protein in autoinflammatory diseases

, 2018
L'interleukine (IL) 18 est une cytokine pro-inflammatoire naturellement inhibée par l'IL-18 binding protein (IL-18BP). Cette dernière est présente en grande quantité dans la circulation et lie l'IL-18 avec une forte affinité, si bien que la majorité de l'IL-18 circule sous une forme inactive non seulement à l'état basal, mais aussi dans de nombreuses ...
openaire   +1 more source