Results 181 to 190 of about 898,035 (301)

Weal and woe of interleukin-18 in the T cell therapy of cancer. [PDF]

J Immunother Cancer
Kessel C, Rossig C, Abken H.
europepmc   +1 more source

Erratum: [Corrigendum] Mesenchymal stem cells expressing interleukin‑18 suppress breast cancer cells in vitro. [PDF]

Exp Ther Med, 2023
Liu X, Hu J, Sun S, Li F, Cao W, Wang Y, Ma Z, Yu Z.   +7 more
europepmc   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

High expression of interleukin-18 receptor alpha correlates with severe respiratory viral disease and defines T cells with reduced cytotoxic signatures. [PDF]

Nat Commun
Cabug AF, Crawford JC, McQuilten HA, Foo IJH, Allen LF, Gebregzabher D, Mettelman RC, Novak T, Chou J, Rowntree LC, Hagen RR, Thomson AJ, Martin GE, Gilbertson B, Souter MN, James F, Goodall E, Rizzetto S, Flerlage T, Jia X, Van de Velde LA, Chang SY, Luciani F, Thwaites RS, Trubiano JA, Kotsimbos TC, Cheng AC, Randolph AG, Thomas PG, Xu J, Wang Z, Nguyen THO, Chua BY, Kedzierski L, Kedzierska K.   +34 more
europepmc   +1 more source

Causal relationship between asthma and ulcerative colitis and the mediating role of interleukin-18: a bidirectional Mendelian study and mediation analysis. [PDF]

Front Immunol, 2023
Zou X, Lu RL, Liao B, Liu SJ, Dai SX.
europepmc   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

The Effect of Coronary Artery Bypass Surgery on Interleukin-18 Concentration and Biomarkers Related to Vascular Endothelial Glycocalyx Degradation. [PDF]

Int J Mol Sci
Knežević D, Batičić L, Ćurko-Cofek B, Batinac T, Ljubačev A, Valenčić Seršić L, Laškarin G, Zdravković M, Šoštarič M, Sotošek V.   +9 more
europepmc   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Salivary Interleukin-6 and Interleukin-18 Levels and Their Association with Dental Health in Children with Idiopathic Nephrotic Syndrome. [PDF]

Int J Mol Sci
Piekoszewska-Ziętek P, Korytowska-Przybylska N, Pańczyk-Tomaszewska M, Olczak-Kowalczyk D.   +3 more
europepmc   +1 more source

Possible Link between Serotonin and Interleukin 18 on Suicidality in Patients with Acute Coronary Syndrome. [PDF]

Clin Psychopharmacol Neurosci, 2023
Kim JM, Kang HJ, Kim JW, Choi W, Kim SW, Kim JC, Chun BJ, Ahn Y, Jeong MH.   +8 more
europepmc   +1 more source