Results 11 to 20 of about 595,005 (302)
Interleukin-18 and interleukin-18 Binding Protein [PDF]
Frontiers in Immunology, 2013 Interleukin-18 (IL 18) is a member of the IL 1 family of cytokines. Increasing reports have expanded the role of IL 18 in mediating inflammation in animal models of disease using IL 18 deficient mice, neutralization of IL 18 or deficiency in the IL 18 ...
Charles eDinarello +6 more
doaj +6 more sources
Interleukin 18 in the CNS [PDF]
Journal of Neuroinflammation, 2010 Interleukin (IL)-18 is a cytokine isolated as an important modulator of immune responses and subsequently shown to be pleiotropic. IL-18 and its receptors are expressed in the central nervous system (CNS) where they participate in neuroinflammatory ...
Sugama Shuei +3 more
doaj +9 more sources
Journal of Leukocyte Biology, 2003 Abstract Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses. IL-18 is expressed at sites of chronic inflammation, in autoimmune diseases, in a variety of cancers, and in the context of numerous infectious diseases.
Gracie, J.A. +2 more
core +6 more sources
Interleukin‑17A and Interleukin‑18 level in the blood serum of patients with different clinical course of Rosacea [PDF]
Archives of the Balkan Medical Union, 2018 Introduction. Rosacea is a common chronic dermatosis characterized by lesions of open areas of the skin (face) and torpidity to treatment. The objective of our study was to determine and analyze the content of proinflammatory cytokines – interleukin‑17A
Maryna V. STOROZHUK, Olha I. DENYSENKO
doaj +3 more sources
The role of interleukin-18 and interleukin-18 binding protein in K/BxN serum transfer-induced arthritis [PDF]
Frontiers in Immunology, 2023 BackgroundInterleukin-18 is a proinflammatory cytokine, the activity of which is regulated by its natural inhibitor, IL-18 binding protein (IL-18BP). Elevated circulating levels of IL-18 have been observed in patients with systemic juvenile idiopathic ...
Sebastien Fauteux-Daniel +17 more
doaj +3 more sources
Interleukin-18: Perspectives on the Newest Interleukin [PDF]
Cytokine & Growth Factor Reviews, 1998 Just over two years ago the newest member of the interleukin family of cytokines, IL-18, was molecularly cloned. IL-18 was originally identified as a result of its ability to induce interferon gamma production, however with the advent of its cloning and the production of recombinant protein a number of other biological actions have since been ...
Gillespie, M T, Horwood, N J
openaire +4 more sources
Increased Expression of Interleukin-18 mRNA is Associated with Carotid Artery Stenosis [PDF]
Balkan Medical Journal, 2018 Background: Carotid artery stenosis is the atherosclerotic narrowing of the proximal internal carotid artery and one of the primary causes of stroke. Elevated expression of the pleiotropic proinflammatory cytokine interleukin-18 has been demonstrated in ...
Berk Arapi +6 more
doaj +2 more sources
Proinflammatory cytokines interleukin-18 and interleukin-6 mediate anorexia induction by trichothecene deoxynivalenol and its congeners [PDF]
Frontiers in Veterinary ScienceAs the common foodborne mycotoxins with the highest pollution rate, deoxynivalenol (DON, also named “vomitoxin”) can harm the health of humans and animals by causing anorectic response.
Chuang Zhou +8 more
doaj +2 more sources
Serum interleukin 18 level in kidney diseases and age [PDF]
Urology AnnalsBackground: Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene, it is a member of the IL 1 family and has a molecular weight of 18 kDa.
Ghada Abd Eltawab Radwan +2 more
doaj +2 more sources
Role of interleukin 15 and interleukin 18 in inflammatory response [PDF]
Annals of the Rheumatic Diseases, 2002 Interleukin 15 (IL15) and interleukin 18 (IL18) are cytokines produced principally by macrophages during innate immune response and subsequently profoundly influence adaptive immunity. Recent studies have shown that IL15 and IL18 play an influential part in inflammatory response. Here we present recent data mainly from our own laboratories illustrating
F Y, Liew, I B, McInnes
openaire +4 more sources