Results 21 to 30 of about 595,005 (302)

Interleukin 18 and interleukin 22 as important immune markers in patients with tuberculosis [PDF]

open access: yesE3S Web of Conferences, 2023
Tuberculosis (TB) is a lung infection caused by the bacterium Mycobacterium tuberculosis (MTB). TB is a leading cause of death globally, accounting for approximately 1.5 million deaths per year.
Kamoona Firas Mohammad Hussein   +1 more
doaj   +1 more source

Interleukin 18 in Immune-mediated rheumatic diseases and COVID-19

open access: yesНаучно-практическая ревматология, 2022
Immune-mediated rheumatic diseases (IMRDs), based on the leading mechanisms of pathogenesis, are conditionally classified into autoimmune, autoinflammatory, and «mixed pattern».
E. L. Nasonov, A. S. Avdeeva
doaj   +1 more source

The comparison of the salivary concentration of interleukin-17 and interleukin-18 in patients with chronic periodontitis and healthy individuals

open access: yesDental Research Journal, 2020
Background: Regarding the prevalence and importance of periodontal disease and the potential of salivary biomarkers for the early diagnosis of these diseases, this study was conducted to compare salivary concentrations of Interleukin-17 (IL-17) and ...
Surena Vahabi   +2 more
doaj   +1 more source

Interleukin-18 and COVID-19 [PDF]

open access: yesEpidemiology and Infection, 2021
Abstract Vulnerability to coronavirus disease (COVID)-19 varies due to differences in interferon gamma (IFNγ) immunity. We investigated whether a key modifiable interferon precursor, interleukin-18, was related to COVID-19, overall and by severity, using Mendelian randomisation.
C. M. Schooling, M. Li, S. L. Au Yeung
openaire   +2 more sources

Interaction between the inflammasome and commensal microorganisms in gastrointestinal health and disease

open access: yesEMBO Molecular Medicine, 2021
The inflammasome is a cytosolic multiprotein complex that plays a crucial role in inflammation and cell death. The sensor proteins in the inflammasome complex detect various microbial and endogenous stimuli, leading to subsequent caspase activation.
Daisuke Watanabe   +2 more
doaj   +1 more source

GSDMD contributes to myocardial reperfusion injury by regulating pyroptosis

open access: yesFrontiers in Immunology, 2022
BackgroundGasdermin D (GSDMD) plays an essential role in the pathway of pyroptosis. However, whether GSDMD participates in myocardial ischaemia/reperfusion injury (MI/RI) remains poorly understood.MethodsSerum levels of GSDMD and IL-18 in ST-segment ...
Xiaomiao Ye   +8 more
doaj   +1 more source

cDNA Cloning of Biologically Active Chicken Interleukin-18 [PDF]

open access: yes, 2000
By searching a chicken EST database, we identified a cDNA clone that appeared to contain the entire open reading frame (ORF) of chicken interleukin-18 (ChIL-18).
Stäheli, Peter   +15 more
core   +1 more source

Interleukin-18

open access: yesInternational Heart Journal, 2018
A prospective observational study was conducted to evaluate the predictive value of interleukin-18 (IL-18) for major adverse cardiovascular events (MACEs) in hemodialysis patients. A total of 85 participants (45 hemodialysis patients and 40 healthy volunteers) with a mean age of 56.3 years were enrolled in this study. Demographic and clinical data were
Wang, Shiying   +3 more
openaire   +4 more sources

Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophrenia

open access: yesJournal of Neuroinflammation, 2012
Background The pleiotropic pro-inflammatory cytokine Interleukin (IL)-18 has been proposed to play a role in schizophrenia, since elevated circulating levels of its protein and altered frequencies of genetic variants in its molecular system are reported ...
Palladino Ilaria   +7 more
doaj   +1 more source

Placentas from Women with Late-Onset Preeclampsia Exhibit Increased Expression of the NLRP3 Inflammasome Machinery

open access: yesBiomolecules, 2023
Pre-eclampsia is a harmful and potentially lethal medical condition during pregnancy clinically diagnosed by hypertension and commonly accompanied by proteinuria and multiorgan affections.
Luis M. Garcia-Puente   +13 more
doaj   +1 more source

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