Results 21 to 30 of about 63,552,420 (203)

Pro-inflammatory interleukin-18 increases Alzheimer’s disease-associated amyloid-β production in human neuron-like cells [PDF]

open access: yes, 2012
Background: Alzheimer’s disease (AD) involves increased accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles as well as neuronal loss in various regions of the neocortex.
Anderson, G.   +14 more
core   +2 more sources

Interleukin-18 and interleukin-18 receptor-α expression in allergic asthma [PDF]

open access: yesEuropean Respiratory Journal, 2011
To the Editors: The inflammatory process in allergic asthma is initiated by T-helper (Th) type-2 cells, which produce a repertoire of cytokines, including interleukin (IL)-4, IL-5, IL-9 and IL-13, which are necessary for immunoglobulin (Ig)E production, airway eosinophilia and goblet cell hyperplasia [1].
H, Imaoka   +10 more
openaire   +2 more sources

Physiological and molecular effects of interleukin-18 administration on the mouse kidney

open access: yesJournal of Translational Medicine, 2018
Background The cytokine interleukin-18 was originally identified as an interferon-γ-inducing proinflammatory factor; however, there is increasing evidence to suggest that it has non-immunological effects on physiological functions.
Kyosuke Yamanishi   +13 more
doaj   +1 more source

Expression of interleukin-18 receptor in fibroblast-like synoviocytes [PDF]

open access: yes, 2001
An excess of the proinflammatory substance IL-18 is present in joints of patients with rheumatoid arthritis (RA), and expression of IL-18 receptor (IL-18R) regulates IL-18 bioactivity in various cell types.
Hoelzer, Dieter (Prof. Dr.)   +15 more
core   +1 more source

Serum interleukin 18 and interleukin 18 binding protein in rheumatoid arthritis [PDF]

open access: yesAnnals of the Rheumatic Diseases, 2002
To measure serum interleukin 18 (IL18) and IL18 binding protein (IL18BP) levels in patients with inflammatory arthropathies, and to identify associations with disease status and the response to treatment.Serum samples were obtained before and after methotrexate treatment from patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA ...
B, Bresnihan   +5 more
openaire   +3 more sources

Diagnostic values of serum IL-17A and IL-18 in Rheumatoid arthritis and Correlation with treatment

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2022
Background: Rheumatoid arthritis (RA) is an autoimmune disorder that involves autoantibodies attacking and weakening joints. RA is characterized by leukocyte (Monocyte, Lymphocyte mast cell .etc) infiltrations into the synovial compartment leading to ...
Noorhan H. Yousif   +2 more
doaj   +1 more source

Priming by recombinant chicken interleukin-2 induces selective expression of IL-8 and IL-18 mRNA in chicken heterophils during receptor-mediated phagocytosis of opsonized and nonopsonized Salmonella enterica serovar enteritidis [PDF]

open access: yes, 2003
Heterophils, the principal avian polymorphonuclear leukocytes (PMNs) equivalent to the mammalian neutrophil, function as professional phagocytes against bacterial infections, mediate acute inflammation, and respond to cytokine stimulation to aid in ...
Michael H Kogut   +5 more
core   +1 more source

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]

open access: yes, 2012
BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.
Thomas, GN   +489 more
core   +1 more source

Interleukin 10 And 18 levels in Essential Hypertensive

open access: yesJournal of Applied Sciences and Environmental Management, 2019
The mechanism underlying a sustained blood pressure elevation and its sequelae on the inflammatory cascades have not been totally unraveled. This research was, in addition to body mass index (BMI), systolic and diastolic blood pressure (SBP and DBP ...
O.O. Odewusi, H.B. Osadolor
doaj   +1 more source

Human mid-gestation amniotic fluid contains interleukin-16 bioactivity [PDF]

open access: yes, 2009
CD4-positive cells are detectable in the human fetal gastrointestinal tract from 11 weeks of gestation. Interleukin-16 (IL-16) is a chemoattractant for CD4(+) cells and, via fetal swallowing of amniotic fluid, could mediate the influx of CD4(+) cells ...
Warner, J.   +17 more
core   +1 more source

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