Results 201 to 210 of about 238,614 (342)

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

Advanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao, Chao Yan, Haibo Huang, Shilong Wang, Jiaying Li, Yun Chen, Xiaolu Qu, Qi Bao, Lingna Xu, Yuanyuan Zhang, Danyang Fan, Xia He, Yanwen Liu, Yongsheng Zhang, Yalan Yang, Zhonglin Tang   +15 more
wiley   +1 more source

Relationship of Interleukin-1 Receptor Antagonist to Mucosal Inflammation in Inflammatory Bowel Disease

, 1995
Jeffrey S. Hyams, John E. Fitzgerald, Nancy Wyzga, Richard Müller, William R. Treem, Christopher J. Justinich, Donald L. Kreutzer   +6 more
openalex   +1 more source

Interleukin-1 Receptor Antagonist Synthesis by Peripheral Blood Mononuclear Cells [PDF]

, 2000
Vaidyanathapuram S. Balakrishnan, Christopher H. Schmid, Bertrand L. Jaber, S Natov, Andrew J. King, Brian J.G. Pereira   +5 more
openalex   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Possible Different Involvement of Interleukin-1 Receptor Antagonist Gene Polymorphism in Coronary Single Vessel Disease and Myocardial Infarction [PDF]

, 2000
Licia Iacoviello, Maria Benedetta Donati, Marinella Gattone   +2 more
openalex   +1 more source

Mesenchymal Stem Cell‐Derived Interleukin 1 Receptor Antagonist Promotes Macrophage Polarization and Inhibits B Cell Differentiation

Stem Cells, 2015
P. Luz-Crawford, F. Djouad, K. Toupet, C. Bony, M. Franquesa, M. Hoogduijn, C. Jorgensen, D. Noël   +7 more
semanticscholar   +1 more source

Fish Swim Bladder‐Derived ECM Hydrogels Effectively Treat Myocardial Ischemic Injury through Immunomodulation and Angiogenesis

Advanced Science, EarlyView.
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu, Canran Gao, Hailing Zhang, Jing Liu, Boxuan Li, Wei Chen, Xiuping Chen, Xue Lin, Ligang Fang, Zhihong Wang   +9 more
wiley   +1 more source

A Bio‐Responsive Hydrogel with Spatially Heterogeneous Structure for Treating Infectious Tissue Injuries

Advanced Science, EarlyView.
The hydrogel incorporates Ag⁺‐loaded Preyssler‐type polyoxometalates (POMs) that release Ag⁺ ions in response to endogenous Na⁺ ions, ensuring controlled antibacterial activity. The spatially heterogeneous structure, created through dual‐channel fiber stacking and in situ cross‐linking, enhances structural integrity and promotes tissue regeneration ...
Zongtai Li, Tao Yang, Xiaolei Li, Panchao Yin, Bo Yang, Dongying Li, Yan Wang, Wei Teng, Qianqian Yu, Weichang Li   +9 more
wiley   +1 more source

Elevation of Interleukin 1 Receptor Antagonist in the Stratum Corneum of Sun-exposed and Ultraviolet B-irradiated Human Skin

, 1996
Tetsuji Hirao, Hiroe Aoki, Tomoko Yoshida, Yoshihisa Sato, H. Kamoda   +4 more
openalex   +1 more source

Interleukin-1 Receptor Antagonist Ribonucleic Acid and Protein Expression by Cultured Graves’ and Normal Orbital Fibroblasts Is Differentially Modulated by Dexamethasone and Irradiation¹ [PDF]

, 2000
Tina Mühlberg, Werner Joba, Christine Spitzweg, Hermann-Dieter Schworm, Hans-Jürgen Heberling, Armin E. Heufelder   +5 more
openalex   +1 more source