Interleukin-1 Receptor Antagonist Gene Polymorphism, Vaginal Interleukin-1 Receptor Antagonist Concentrations, and VaginalUreaplasma urealyticumColonization in Pregnant Women [PDF]
Parrin Tareyl Barton+3 more
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Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu+13 more
wiley +1 more source
Potential therapeutic uses of interleukin 1 receptor antagonists in human diseases [PDF]
David S. Hallegua
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Interleukin‐1 Receptor Antagonist Gene Polymorphism and Cancer [PDF]
Sehouli Jalid, Alexander Mustea
openaire +3 more sources
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu+10 more
wiley +1 more source
Local Expression of Interleukin-1 Receptor Antagonist by Plasmid DNA Improves Mortality and Decreases Myocardial Inflammation in Experimental Coxsackieviral Myocarditis [PDF]
Byung‐Kwan Lim+7 more
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A self‐propelled nanomedicine delivery system forms DMCU nanoparticles in the bladder via in situ polymerization of dopamine hydrochloride, Mn2+, cGAMP, and urease. The urease‐driven propulsion enhances retention and drug delivery. These nanoparticles activate the STING pathway, stimulating dendritic cells and T cells to boost anti‐bladder cancer ...
Lei Peng+9 more
wiley +1 more source
Interleukin‐1 Receptor Antagonist Gene Polymorphism, Infectious Burden, and Coronary Artery Disease [PDF]
Johann Auer+3 more
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Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang+6 more
wiley +1 more source
1157. Suppression of Collagen-Induced Arthritis by Intramuscular Gene Therapy with Plasmid DNA Expressing the Interleukin-1 Receptor Antagonist [PDF]
openalex +1 more source