Results 71 to 80 of about 238,614 (342)
Circulation Journal, 2009 Interleukin (IL)-beta plays a central role in inflammation and atherosclerosis, but levels of IL-1beta, its natural antagonist, IL-1Ra, and their balance in human atherosclerotic lesions, are unknown. Knowledge of protein levels in atherosclerosis and the influence of a functional IL-1Ra polymorphism would increase the understanding of atherosclerosis ...
Peder S. Olofsson +8 more
openaire +4 more sources
Interleukin Gene Marker for Febrile Seizures
Pediatric Neurology Briefs, 2002 The use of polymorphisms for interleukin IB (IL-1B) exon 5 and interleukin 1 receptor antagonist (IL-1Ra) as markers of susceptibility to febrile seizures was evaluated in Taiwanese children (group 1: 51 with febrile convulsions and group 2: 83 normal ...
J Gordon Millichap
doaj +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Journal of Cerebral Blood Flow and Metabolism, 2015 Stroke represents a global challenge and is a leading cause of permanent disability worldwide. Despite much effort, translation of research findings to clinical benefit has not yet been successful. Failure of neuroprotection trials is considered, in part,
S. Maysami +14 more
semanticscholar +1 more source
Cannabinoid signalling in TNF-alpha induced IL-8 release [PDF]
, 2006 Original article can be found at: http://www.sciencedirect.com/science/journal/00142999 Copyright Elsevier B.V.
Baydoun, A. R. +4 more
core +1 more source
Вопросы современной педиатрии, 2016 The article describes the main autoinflammatory syndromes as well as the key role of interleukin (IL) 1 in the pathogenesis of these diseases. It also presents the data on the experience of anakinra using (soluble IL-1 receptor antagonist) as well as the
Mikhail M. Kostik
doaj +1 more source
Alterations in the interleukin-1/interleukin-1 receptor antagonist balance modulate cardiac remodeling following myocardial infarction in the mouse. [PDF]
PLoS ONE, 2011 Healing after acute myocardial infarction (AMI) is characterized by an intense inflammatory response and increased Interleukin-1 (IL-1) tissue activity. Genetically engineered mice lacking the IL-1 receptor (IL-1R1-/-, not responsive to IL-1) or the IL-1
Antonio Abbate +7 more
doaj +1 more source
Frontiers in Immunology, 2023 BackgroundThe interleukin-1 pathway has been linked to pancreatic diseases. We applied the Mendelian randomization approach to explore whether higher interleukin-1 receptor antagonist (IL-1RA) levels reduce the risk of acute and chronic pancreatitis and ...
Shuai Yuan +7 more
doaj +1 more source
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1 beta inhibition [PDF]
, 2006 BACKGROUND:Neonatal-onset multisystem inflammatory disease is characterized by fever, urticarial rash, aseptic meningitis, deforming arthropathy, hearing loss, and mental retardation.
Adams, BS +39 more
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