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Understanding the relationship between lung GABA<sub>A</sub> receptors and aquaporin-1: a new therapeutic approach for acute lung injury. [PDF]
BMC Pulm MedHalici H +5 more
europepmc +1 more source
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Successful treatment of Erdheim-Chester disease by interleukin-1 receptor antagonist protein
Joint Bone Spine, 2014Erdheim-Chester disease is a rare non-langerhans systemic histiocytosis of unknown origin, associated with bone diseases and severe visceral complications. Therapies have been disappointing. A recombinant form of interleukin-1 receptor antagonist (anakinra) has been used in a few cases when usual treatment fails.
Roland Chapurlat
exaly +3 more sources
Cytokine, 2000
Hypoxic pulmonary vasoconstriction is associated with but may not be sufficient for the development of high-altitude pulmonary oedema (HAPO). Hypoxia is known to induce an inflammatory response in immune cells and endothelial cells. It has been speculated that hypoxia-induced inflammatory cytokines at high altitude may contribute to the development of ...
Matthias Tschop
exaly +3 more sources
Hypoxic pulmonary vasoconstriction is associated with but may not be sufficient for the development of high-altitude pulmonary oedema (HAPO). Hypoxia is known to induce an inflammatory response in immune cells and endothelial cells. It has been speculated that hypoxia-induced inflammatory cytokines at high altitude may contribute to the development of ...
Matthias Tschop
exaly +3 more sources
Cytokine regulation of the interleukin-1 receptor antagonist protein in U937 cells
European Journal of Immunology, 1993AbstractA naturally occurring receptor‐level antagonist of interleukin‐1 (IRAPorIL‐1 ra) has recently been cloned. To determine what stimuli might regulate this inhibitor, cytokines were tested for their effects on the steady‐state level of IRAP mRNA in phorbol ester‐differentiated U937 cells.
A E Berger, D B Carter
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Treatment With an Interleukin-1 Receptor Antagonist Protein Prolongs Mouse Islet Allograft Survival
Diabetes, 1993An interleukin-1 receptor antagonist protein was evaluated with regard to its efficacy in allogeneic and xenogeneic islet transplantation. Alloxan-induced diabetic C57BL/6 (H-2b) mice were transplanted under the kidney capsule with 500 C57BL/Ks (H-2d) mouse islets.
Decio L Eizirik +2 more
exaly +4 more sources
Counteracting corneal immunoinflammatory lesion with interleukin-1 receptor antagonist protein
Journal of Leukocyte Biology, 2004AbstractHerpetic stromal keratitis (HSK) is a T cell-orchestrated, immunoinflammatory lesion that results from corneal Herpes simplex virus infection. Previous reports indicate an essential role for proinflammatory cytokine interleukin (IL)-1 in HSK pathogenesis.
Partha Sarathi, Biswas +3 more
openaire +2 more sources
Interleukin-1 Receptor Antagonist Protein and mRNA in the Rat Adrenal Gland
Journal of Interferon & Cytokine Research, 1995The occurrence of the endogenous receptor antagonist for the cytokine interleukin-1 in the rat adrenal gland was analyzed y polymerase chain reaction and by immunohistochemistry using a rabbit polyclonal antiserum. Expression of interleukin-1 receptor antagonist mRNA was demonstrated in both adrenal medulla and cortex, and a marked increase in the ...
M, Schultzberg +6 more
openaire +2 more sources