Results 171 to 180 of about 22,989,400 (391)

Capitalizing on opportunities and changing course: An experimental cell line model for T cell activation revealed a two signal model for Interleukin 2 transcript accumulation

Frontiers in Immunology, 2015
Arthur eWeiss, John D Stobo
doaj   +1 more source

Interleukin 1-dependent induction of both interleukin 2 secretion and interleukin 2 receptor expression by thymoma cells. [PDF]

, 1986
John W. Lowenthal, J C Cerottini, H. Robson MacDonald   +2 more
openalex   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Experience with the Use of High-Dose Interleukin-2 in the Treatment of 652 Cancer Patients

, 1989
Steven A. Rosenberg, Michael T. Lotze, James Chih‐Hsin Yang, Paul Aebersold, W. Marston Linehan, Claudia A. Seipp, Donald E. White   +6 more
openalex   +2 more sources

Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2. [PDF]

, 1983
N Nogueira, Gilla Kaplan, Elinor M. Levy, Euzenir Nunes Sarno, P. D. Kushner, Angela Granelli‐Piperno, Letícia Vieira, V Colomer Gould, William R. Levis, Ralph M. Steinman   +9 more
openalex   +1 more source

Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro

Advanced Healthcare Materials, EarlyView.
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski, Svenja Nellinger, Franziska Brigitte Albrecht, Petra Juliane Kluger   +3 more
wiley   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

The contribution of interleukin-2 to effective wound healing

Experimental biology and medicine, 2017
K. M. Doersch, Daniel J DelloStritto, M. Newell-Rogers   +2 more
semanticscholar   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

Advanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja, Lubaba A. Zaman, Chen Zhang, Milankumar Patel, Santhi Gorantla, Prasanta K. Dash, Howard E. Gendelman   +6 more
wiley   +1 more source

Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression

HYPERTENSION, 2016
Huan Wang, Lei Hou, Dongmin Kwak, J. Fassett, Xin Xu, A. Chen, W. Chen, B. Blazar, Yawei Xu, Jennifer L. Hall, Jun-bo Ge, R. Bache, Yingjie Chen   +12 more
semanticscholar   +1 more source