T cell-specific suppressor factor(s) with regulatory influence on interleukin 2 production and function [PDF]
, 1982 In this study we report that alloantigen-activated spleen cells produce both amplifying and suppressive factors under the same conditions. Both types of soluble mediators--as detected in different assay systems-- were present in the supernatants of in ...
Koszinowski, Ulrich H., Kramer, M.
core
Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
Advanced Healthcare Materials, EarlyView.Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou +4 more
wiley +1 more source
Advanced Materials, EarlyView.A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen +7 more
wiley +1 more source
Recalcitrant lupus miliaris disseminatus faciei improved by cyclosporine monotherapy
JAAD Case Reports, 2022 Hyeok-Jin Kwon, MD +5 more
doaj
Compartmentalized activation of the interleukin 2 gene by lung T lymphocytes in active pulmonary sarcoidosis. [PDF]
, 1986 Joachim Müller‐Quernheim +3 more
openalex +1 more source
Advanced Materials, EarlyView.Wearable sensors, empowered by AI and smart materials, revolutionize healthcare by enabling intelligent disease diagnosis, personalized therapy, and seamless health monitoring without disrupting daily life. This review explores cutting‐edge advancements in smart materials and AI‐driven technologies that empower wearable sensors for diagnostics and ...
Shuwen Chen +14 more
wiley +1 more source
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Lymphokine-activated tumor inhibition in vivo. I. The local administration of interleukin 2 triggers nonreactive lymphocytes from tumor-bearing mice to inhibit tumor growth. [PDF]
, 1985 G Forni +2 more
openalex +1 more source
Surface Functionalized Ti3CNTx MXene for Monitoring Sweat pH with Superhydrophobic Protection
Advanced Materials Interfaces, EarlyView.The highly sensitive, stable, and superhydrophobic pH sensor is made by functionalizing the Ti3CNTx MXene surface with fluoroalkyl silane grafting. This strategy is expected to push forward the application of MXene in sweat pH sensing in the near future. Abstract Real‐time tracking of metabolites, ions, and biomarkers in sweat using wearable sensors is
Hui Yang +7 more
wiley +1 more source