Results 271 to 280 of about 22,989,400 (391)

Interleukin‐2/anti‐interleukin‐2 monoclonal antibody immune complex suppresses collagen‐induced arthritis in mice by fortifying interleukin‐2/STAT5 signalling pathways

Immunology, 2012
Seon-Yeong Lee, M. Cho, H. Oh, J. Ryu, Min-jung Park, J. Jhun, Mi-Kyung Park, J. Stone, Ji‐hyun Ju, Sue‐Yun Hwang, Sung-Hwan Park, C. Surh, Ho‐Youn Kim   +12 more
semanticscholar   +1 more source

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

Advanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen, Yijun Lin, Xinyu Zhu, Shixuan Zhuo, Zixuan Li, Cheng Guo, Xiaoyi Ye, Jinzhu Chen, Shuying Wang, Yan Chen   +9 more
wiley   +1 more source

Interleukin-2-induced skin inflammation. [PDF]

Eur J Immunol
Sommer C, Cohen JN, Dehmel S, Neuhaus V, Schaudien D, Braun A, Sewald K, Rosenblum MD.   +7 more
europepmc   +1 more source

Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity

Advanced Science, EarlyView.
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi, Claudia Corbo, Julia Enterria‐Rosales, John Otto Martinez, Silvia Minardi, Laura Pandolfi, Xing Wang, Ennio Tasciotti, Kavindra V. Singh, Cesar A. Arias, Bruna Corradetti   +10 more
wiley   +1 more source

The IL-2/IL-2-Receptor Complex in the Maturation of Rat T-Cell Progenitors

Clinical and Developmental Immunology, 1998
Alberto Varas, Teresa Romo, Eva Jiménez, Luis Alonso, Angeles Vicente, Agustín G. Zapata   +5 more
doaj   +1 more source

Multiple Tumors in a Patient with Interleukin-2-Inducible T-Cell Kinase Deficiency: A Case Report. [PDF]

Int J Mol Sci
Di Filippo M, Tallone R, Muraca M, Pelanconi L, Faravelli F, Capra V, De Marco P, Ognibene M, Baldassari S, Terranova P, Livellara V, Vellone VG, Miano M, Amoroso L, Beccaria A.   +14 more
europepmc   +1 more source

Interleukin-2 Initiates Metabolic Responses Associated with Critical Illness in Humans

, 1988
H. R. Michie, Timothy J. Eberlein, David R. Spriggs, Kirk R. Manogue, Anthony Cerami, Douglas W. Wilmore   +5 more
openalex   +2 more sources

Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells.

Immunity, 2010
M. Pipkin, J. Sacks, Fernando Cruz-Guilloty, M. Lichtenheld, M. Bevan, A. Rao   +5 more
semanticscholar   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source