Results 11 to 20 of about 3,531,639 (330)

Interleukin 21 Reinvigorates the Antiviral Activity of Hepatitis B Virus (HBV)–Specific CD8+ T Cells in Chronic HBV Infection [PDF]

Journal of Infectious Diseases, 2018
BACKGROUND Strategies that target functional recovery of exhausted hepatitis B virus (HBV)-specific CD8+ T cells are beneficial for viral control, but the potential for interleukin 21 (IL-21) to rescue CD8+ T-cell function is not well understood ...
Libo Tang, Chengcong Chen, Xueping Gao, Wanyue Zhang, Xin Yan, Yang Zhou, Ling Guo, Xinchun Zheng, Weibin Wang, Fuqiang Yang, Guangze Liu, Jian Sun, Jinlin Hou, Yongyin Li   +13 more
openalex   +2 more sources

Tfh-cell-derived interleukin 21 sustains effector CD8⁺ T cell responses during chronic viral infection. [PDF]

Immunity, 2022
Zander R, Kasmani MY, Chen Y, Topchyan P, Shen J, Zheng S, Burns R, Ingram J, Cui C, Joshi N, Craft J, Zajac A, Cui W.   +12 more
europepmc   +2 more sources

Obesity and childhood asthma in male schoolchildren in Saudi Arabia: Is there a role for leptin, interleukin-4, interleukin-5, and interleukin-21? [PDF]

Ann Saudi Med, 2019
BACKGROUND: Adiposity is associated with high serum levels of adipokines and chemokines which are possibly implicated in a co-existence of obesity and asthma.
Al-Ayed M, Alshaybari K, Alshehri D, Jamaan A, Nasser I, Alaamri H, Alaseeri W, Mahfouz AA, Ali Alsareli S, Asaad AM, Ali Magzoub A, Qureshi MA, Shalayel MH.   +12 more
europepmc   +2 more sources

Interleukin-21 Signaling: Functions in Cancer and Autoimmunity [PDF]

Clinical Cancer Research, 2007
Abstract Interleukin-21 (IL-21) is a cytokine with structural and sequence homology to IL-2 and IL-15, yet possesses several biological properties distinct from these cytokines. IL-21 is produced mainly by activated CD4+ T cells and natural killer T cells and mediates its activity by binding to the IL-21 receptor (IL-21R), consisting of ...
Ian D. Davis, Kresten Skak, Mark J. Smyth, Paul E.G. Kristjansen, Dennis M. Miller, Pallavur V. Sivakumar   +5 more
openalex   +5 more sources

Interleukin 21 Receptor Affects Adipogenesis of Human Adipose-Derived Stem/Stromal Cells. [PDF]

Stem Cells Int, 2022
Falavinha BC, Barisón MJ, Rebelatto CLK, Marcon BH, de Melo Aguiar A, da Silva EB, Stimamiglio MA, Shigunov P.   +7 more
europepmc   +3 more sources

Interleukin-21 signaling

Reactome - a curated knowledgebase of biological pathways, 2017
The IL21 heteromeric receptor complex can activate JAK1 and JAK3 in response to Interleukin-21 (IL21), leading to JAK tyrosine phosphorylation (Asao et al. 2001, Habib et al. 2002).
B. Meldal, S. Jupe
semanticscholar   +2 more sources

Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD. [PDF]

Cancer Cell
Shanley M, Daher M, Dou J, Li S, Basar R, Rafei H, Dede M, Gumin J, Pantaleόn Garcίa J, Nunez Cortes AK, He S, Jones CM, Acharya S, Fowlkes NW, Xiong D, Singh S, Shaim H, Hicks SC, Liu B, Jain A, Zaman MF, Miao Q, Li Y, Uprety N, Liu E, Muniz-Feliciano L, Deyter GM, Mohanty V, Zhang P, Evans SE, Shpall EJ, Lang FF, Chen K, Rezvani K.   +33 more
europepmc   +2 more sources

Interleukin 21 Measurement [PDF]

Definitions, 2020

semanticscholar   +2 more sources

The effects of interleukin-21 in the biology of transplant rejection. [PDF]

Front Immunol
Zeng X, Pan Y, Xia Q, He K.
europepmc   +3 more sources

Interleukin-21 Receptor [PDF]

Definitions, 2020

semanticscholar   +2 more sources