Results 191 to 200 of about 3,531,639 (330)

Anti-CD20-interleukin-21 fusokine targets malignant B cells via direct apoptosis and NK-cell-dependent cytotoxicity.

Blood, 2017
Shruti Bhatt, S. Parvin, Yu Zhang, Hyun-Mi Cho, K. Kunkalla, F. Vega, J. Timmerman, Seung-Uon Shin, J. Rosenblatt, I. Lossos   +9 more
semanticscholar   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Comparison of interleukin-21 levels and its correlation with clinical parameters among healthy individuals, chronic periodontitis, and aggressive periodontitis patients. [PDF]

J Clin Transl Res, 2021
Mootha A, Malaiappan S, Milstein DMJ, Karthikeyan G, Varghese SS, Jayakumar ND.   +5 more
europepmc   +1 more source

Data from Lenalidomide Induces Interleukin-21 Production by T Cells and Enhances IL21-Mediated Cytotoxicity in Chronic Lymphocytic Leukemia B Cells

, 2023
Rebekah L. Browning, William H. Byrd, Nikhil Gupta, Jeffrey A. Jones, Xiaokui Mo, Erin Hertlein, Lianbo Yu, Natarajan Muthusamy, John C. Byrd   +8 more
openalex   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Potential anti-EBV effects associated with elevated interleukin-21 levels: a case report. [PDF]

BMC Infect Dis, 2020
Assing K, Nielsen C, Jakobsen M, Andersen CB, Skogstrand K, Gaini S, Preiss B, Mortensen SB, Skov MN, Rasmussen LD.   +9 more
europepmc   +1 more source

Upregulation of Interleukin 21 and Promotion of Interleukin 17 Production in Chronic or Recurrent Vogt-Koyanagi-Harada Disease

, 2010
Fuzhen Li
openalex   +2 more sources

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Interleukin-21 engineering enhances CD19-specific CAR-NK cell activity against B-cell lymphoma via enriched metabolic pathways. [PDF]

Exp Hematol Oncol
He B, Chen H, Wu J, Qiu S, Mai Q, Zeng Q, Wang C, Deng S, Cai Z, Liu X, Xuan L, Li C, Zhou H, Liu Q, Xu N.   +14 more
europepmc   +1 more source

Association between Interleukin-21 Serum Level and IL-21 Genetic Polymorphism with the Cardiovascular Morbidity Risk in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients [PDF]

openalex   +1 more source