Results 51 to 60 of about 3,088,438 (300)
Cytokines have prominent roles in activating of different T cells and shifting the immune response, in this study the role of three cytokines (IL-21, IL-23 and IL-27) is investigated in the liver transplant rejection.
Afsoon Afshari+6 more
doaj +1 more source
Interleukin-21 accelerates thymic recovery from glucocorticoïd-induced atrophy. [PDF]
Both physiological and psychological stress cause thymic atrophy via glucocorticoïd (GC)-dependent apoptosis of double-positive (DP) thymocytes. Given the pervasiveness of stress, GC-induced thymic atrophy is arguably the most common type of acquired ...
Moutih Rafei+3 more
doaj +1 more source
Chronic Hepatitis B (CHB) affects over 350 million people worldwide. Current treatment does result in reduced complications; however, a cure (development of antibodies to the S antigen) is not achieved, requiring life-long therapy.
Arshi Khanam+4 more
doaj +1 more source
T and B cells have been implicated in hypertension, but the mechanisms by which they produce a coordinated response is unknown. T follicular helper (Tfh) cells that produce interleukin 21 (IL21) promote germinal center (GC) B cell responses leading to ...
B. Dale+22 more
semanticscholar +1 more source
IL‐21 regulates macrophage activation in human monocytic THP‐1‐derived macrophages
Background: Interleukin‐21 (IL‐21) has a regulatory effect on various immune cells. Its effect on macrophage function remains unclear. Aims: This study aimed to investigate the effect of IL‐21 on the macrophages‐mediated inflammatory response and explore
Leilei Jian+7 more
doaj +1 more source
Interleukin-21 in cancer immunotherapy [PDF]
Interleukin (IL)-21, a cytokine produced by activated conventional CD4+ T lymphocytes and Natural Killer T cells, drives anti-tumor immunity in the skin and kidney. However IL-21 is also pro-inflammatory in many tissues and promotes colitis-associated colon cancer.
Stolfi, C+3 more
openaire +4 more sources
Background Kawasaki disease (KD) is a febrile childhood vasculitis of unknown etiology. The diagnosis is highly concerning as over a quarter of children who fail to receive timely treatment with intravenous immunoglobulin (IVIG) will develop coronary ...
Rachel Engelberg+3 more
doaj +1 more source
Memory stem T (TSCM) cells, a new subset of memory T cells with self-renewal and multipotent capacities, are considered as a promising candidates for adoptive cellular therapy.
Yingshi Chen+9 more
semanticscholar +1 more source
Expressions of IL-17, IL-21 and IL-23 in the serum of allergic rhinitis patients [PDF]
The present study aimed to investigate the expressions of interleukin-17 (IL-17), IL-21 and IL-23 in the serum of allergic rhinitis (AR) patients and to explore their relationship with special IgE (sFgE) in the serum.
Huang Xuekun+5 more
doaj
Background: Interleukin-21 (IL-21) modulates HIV-1 infection through the elicitation of different antiviral mechanisms, including Th17 lineage commitment and induction of microRNA (miR)-29, a miRNA endowed with anti-HIV activity.
Paula A S Ortega+12 more
semanticscholar +1 more source