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Interleukin-22

American Journal of Respiratory Cell and Molecular Biology, 2004
Abstract Interleukin (IL)-22 is a member of the human type I interferon family, which includes IL-10. IL-22 has the potential to interact with IL-10 because it binds to the IL-10R2c chain with IL-22R1 in its receptor complex. Binding can be blocked by the soluble receptor, IL-22 binding protein (IL-22BP). We hypothesize that IL-22 and
Hayley A. Whittington   +3 more
openaire   +1 more source

Temporal expression of interleukin‐22, interleukin‐22 receptor 1 and interleukin‐22‐binding protein during experimental periodontitis in rats

Journal of Periodontal Research, 2017
Background and ObjectiveInterleukin‐22 (IL‐22), mainly produced by CD4+ T‐helper subtypes and innate lymphoid cells at barrier surfaces, is found to involve in several diseases, including diabetes, rheumatoid arthritis, peri‐implantitis and chronic rhinosinusitis with nasal polyps.
S. Pan   +6 more
openaire   +2 more sources

The role of interleukin-22 in pityriasis rosea

Clinical and Experimental Dermatology, 2016
Pityriasis rosea (PR) is an exanthematous disease related to reactivation of human herpes virus (HHV) types 6 and 7. The pathogenesis and cytokine profile of PR are still poorly understood.There is a large amount of evidence indicating a viral aetiology for PR.To measure the serum level of interleukin (IL)-22, a cytokine expressed by T helper (Th)17 ...
S. Al Mokadem   +3 more
openaire   +2 more sources

Interleukin-22/Interleukin-22 binding protein axis and oral contraceptive use in polycystic ovary syndrome

Endocrine, 2023
Polycystic ovary syndrome (PCOS) is associated with alterations in gut microbiota. The cytokine interleukin-22 (IL-22) is produced by immune cells and closely linked to gut immunity, which is tightly controlled by its binding protein (IL-22BP). In this study, we aimed to assess whether IL-22/IL-22BP axis is altered in PCOS at baseline and in response ...
Seren Aksun   +3 more
openaire   +2 more sources

Targeting Interleukin-22 in Psoriasis

Inflammation, 2013
Interleukin-22 (IL-22) is an IL-10 family cytokine that was recently discovered to be released by T helper 17 (Th17) cells, Th22 cells, etc. Recently, there is emerging evidence that IL-22 is involved in the development and pathogenesis of psoriasis.
openaire   +2 more sources

A RAPID BIOASSAY FOR RECOMBINANT INTERLEUKIN-22

Journal of Immunoassay and Immunochemistry, 2009
Interleukin-22 is a novel cytokine produced mainly in activated T cells. The elaborate biological functions of IL-22 in vivo are still widely unknown. In this report, we describe a rapid, simple, and reproducible in vitro cell-based bioassay for measuring the bioactivity of recombinant interleukin-22 (IL-22) to study the primary function of IL-22 in ...
Fei, Xu   +5 more
openaire   +2 more sources

Interleukin-22 in kidney injury and regeneration

American Journal of Physiology-Renal Physiology, 2015
Interleukins have become well-known regulators of innate and adaptive immunity-related tissue inflammation. Recently, IL-22 has gained a lot of interest for its unique functions in maintaining and regaining epithelial integrity. IL-22 is exclusively secreted by different immune cell subsets, while IL-22 receptors are mainly expressed by epithelial ...
Marc, Weidenbusch   +2 more
openaire   +2 more sources

Comparison of Interleukin-22 and Interleukin-10 Soluble Receptor Complexes

Journal of Interferon & Cytokine Research, 2002
Interleukin-22 (IL-22) is a cellular homolog of IL-10 that stimulates the production of acute-phase reactants. IL-22 and IL-10 require different ligand-specific receptor chains (IL-22R and IL-10R1) but share a second receptor chain (IL-10R2) to initiate cellular responses.
Naomi J, Logsdon   +4 more
openaire   +2 more sources

Interleukin‐22 and Its Crystal Structure

2006
Interleukin-22 (IL-22) is a cytokine that regulates the production of acute phase proteins of the immunological response. On binding to its cognate receptor (IL-22R1), which is associated to the interleukin-10 receptor 2 (IL-10R2), IL-22 promotes activation of signal transducer and activator of transcription (STAT) pathway and several other cellular ...
Ronaldo Alves Pinto, Nagem   +4 more
openaire   +2 more sources

[Interleukin-20 and interleukin-22 in pleural effusion].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2017
To investigate the concentrations and clinical significance of interleukin (IL)-20 and IL-22 in pleural effusion with various etiologies.Pleural effusion (PE) and corresponding serum samples were obtained from 88 patients from Wuhan Tuberculosis Prevention and Control Institute from June 2011 to June 2013.
T Z, Cao   +4 more
openaire   +1 more source

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