Results 221 to 230 of about 417,438 (262)

Mitigating Teclistamab Toxicity: Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort

American Journal of Hematology, EarlyView.
Astrid Hundebøll Torpe, Jonathan Thorsen, Gustav Mathiasen, Katrine Fladeland Iversen, Sarah Farmer, Thomas Lund, Charlotte Toftmann Hansen, Lene Kongsgaard Nielsen, Nicolai Grønne Dahlager Jørgensen, Maja Ølholm Vase, Elena Manuela Teodorescu, Morten Salomo, Christina Wennerström, Tobias S. Slørdahl, Agoston Gyula Szabo   +14 more
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Interleukin-38 in atherosclerosis

Clinica Chimica Acta, 2022
Chronic inflammation caused by immune cells and their mediators is a characteristic of atherosclerosis. Interleukin-38 (IL-38), a member of the IL-1 family, exerts multiple anti-inflammatory effects via specific ligand-receptor interactions. Upon recognizing a specific receptor, IL-38 restrains mitogen-activated protein kinase (MAPK), nuclear factor ...
Xiao-Hong Zhang, Yu Li, Li Zhou, Guo-Ping Tian   +3 more
openaire   +2 more sources

Assessment of the levels of interleukin-17 and interleukin-38 in thyroid-associated ophthalmopathy patients

International Ophthalmology, 2023
The objective of the study was to analyse the levels of IL-17 and IL-38 in the samples of unstimulated tears, orbital adipose tissues, and sera of patients diagnosed with active forms of TAO. The correlation of the levels of IL-17 and IL-38 with clinical activity score (CAS) was scrutinized.A study was conducted at the Kazakhstan Scientific Research ...
Ainura, Mussakulova, Aigul, Balmukhanova, Alua, Aubakirova, Gulnur, Zhunusova, Altynay, Balmukhanova, Jamilya, Issakhanova, Timur, Saliev, Shynar, Tanabayeva, Ildar, Fakhradiyev   +8 more
openaire   +2 more sources

Biology of interleukin-38 and its role in chronic inflammatory diseases

International Immunopharmacology, 2021
Interleukin (IL)-38 is the tenth member of the IL-1 cytokine family. IL-38 shares high similarity with IL-36Ra and IL-1Ra and can bind to their receptors, thus exerting an anti-inflammatory effect. Despite the lack of a signal peptide, IL-38 can be released from several cell types, but its maturation process remains obscure.
Hua-song Xia, Yue Liu, Yang Fu, Meng Li, Yan-qing Wu   +4 more
openaire   +2 more sources

Plasma interleukin-38 in patients with rheumatoid arthritis

International Immunopharmacology, 2018
Previous studies have indicated that interleukin-38 (IL-38) is involved in rheumatoid arthritis (RA). The present study aims to assess plasma levels of IL-38 in RA and discuss the potential of IL-38 as a biomarker for RA. Protein concentrations of IL-38 were examined by enzyme-linked immunosorbent assay, and the mRNA level of IL-38 was tested by ...
Wang-Dong, Xu, Lin-Chong, Su, Cheng-Song, He, An-Fang, Huang   +3 more
openaire   +2 more sources

Interleukin-38 and Insulin Resistance

Endocrine, Metabolic & Immune Disorders - Drug Targets
Abstract: Insulin resistance, i.e., decreased biological response to insulin, is a risk factor for many diseases, such as obesity, type 2 diabetes (T2DM), cardiovascular disease, polycystic ovary syndrome, some forms of cancer and neurodegenerative diseases.
Kamil Klejbuk, Marek Strączkowski
openaire   +2 more sources

The Effect of Interleukin 38 on Inflammation-induced Corneal Neovascularization

Current Molecular Medicine, 2019
Background: Angiogenesis is tightly linked to inflammation. Cytokines of interleukin 1 (IL-1) family are key mediators in modulating inflammatory responses. Methods: In this study, we examined the role of IL-38, a member of the IL-1 family, in mediating inflammation-induced angiogenesis.
Jiangli, Zhu, Jing, Zhang, Yan, Wang, Jianping, Chen, Xiaopeng, Li, Xiangling, Liu, Eryan, Kong, Shao B, Su, Zhongjian, Zhang   +8 more
openaire   +2 more sources

Investigation of Interleukin-38 in patients with primary Sjögren’s Syndrome

Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, 2022
Aim: Interleukin-38 has been involved as an inflammatory mediator in rheumatic diseases. However, little is known about the role of IL-38 in the development of primary Sjögren’s syndrome. The present study aimed to evaluate the role of IL-38 in primary Sjögren’s syndrome and its clinical relevance.
Selcan GÜLTUNA, Sevinc CAN, Fevzi Nuri AYDİN   +2 more
openaire   +1 more source

Serum interleukin-38 and -41 levels as candidate biomarkers in male infertility

Immunology Letters, 2023
Interleukin (IL)-38 and IL-41 are novel cytokines, but their role in male infertility (MI) is unknown. The purpose of this study was to measure the levels of serum IL-38 and IL-41 in patients with MI and correlate these levels with semen indexes.Eighty-two patients with MI and 45 healthy controls (HC) were recruited for this study.
Chunhao, Rong, Linjie, Weng, Mingcai, Li, Liming, Zhou, Yan, Li   +4 more
openaire   +2 more sources

Interleukin-38 overexpression prevents bleomycin-induced mouse pulmonary fibrosis

Naunyn-Schmiedeberg's Archives of Pharmacology, 2020
Pulmonary fibrosis is a kind of pulmonary disorder with chronic inflammation and excessive collagen deposition, and its etiology is not clear. Interleukin (IL)-38 is a new member of IL-1 family cytokines, but its role in pulmonary fibrosis has not been elucidated.
Zhiwei Xu, Xianli Yuan, Qiaoyan Gao, Yan Li, Mingcai Li   +4 more
openaire   +2 more sources