Zdorovʹe Rebenka, 2018 Background. Broncho-obstructive syndrome (BOS), particularly, its recurrent course in young children, is an important question of modern pediatrics. The burdened allergic history, manifestations of atopy are traditionally considered as risk factors for ...
Yu.K. Bolbot +2 more
doaj +1 more source
Impacts of BMI & IL-4 Genetic Polymorphisms (rs2243250 C/T & rs2227284 A/C) on Iranian Breast Cancer Patients: a Pilot Study [PDF]
Journal of Advanced Biomedical Sciences, 2022 Background & Objective: Breast cancer is a phenotypically complex and diverse genetic disease caused by changes in the structure and expression of specific genes. Immune system factors are also involved in the etiology of this neoplasm.
Samanehsadat Shahidi +1 more
doaj
Reprogramming of lysosomal gene expression by interleukin-4 and Stat6. [PDF]
, 2013 BACKGROUND: Lysosomes play important roles in multiple aspects of physiology, but the problem of how the transcription of lysosomal genes is coordinated remains incompletely understood.
Bartlett, NW +9 more
core +2 more sources
Evaluating the Effect of Interleukin-4 in the 3xTg Mouse Model of Alzheimer’s Disease
Frontiers in Neuroscience, 2020 Chronic neuroinflammation has long been hypothesized to be involved in Alzheimer’s Disease (AD) progression. Previous research suggests that both anti-inflammatory and inflammatory microglia ameliorate amyloid pathology, but the latter worsen tau ...
Dawling A. Dionisio-Santos +3 more
doaj +1 more source
Interleukin-2 therapy in patients with HIV infection [PDF]
, 2009 BACKGROUND Used in combination with antiretroviral therapy, subcutaneous recombinant interleukin-2 raises CD4+ cell counts more than does antiretroviral therapy alone. The clinical implication of these increases is not known.
Aagaard, B. +49 more
core +6 more sources
History of interleukin-4 [PDF]
Cytokine, 2015 The history of the discovery and the development of our knowledge of IL-4 exemplifies the path of progress in biomedical science. There are unanticipated twists and turns although progress is made, sometimes quickly, other times far too slowly. Illustrative is the extended time from the first report of IL-4 in 1982 to the establishment of the efficacy ...
openaire +2 more sources
possible protective role of interleukin-4 in rheumatoid arthritis
مجلة كلية الطب, 2005 Background:
khalidda Al- Mousawy, Al-haidary B A
doaj +1 more source
Interleukin-3 and Interleukin-4 in Childhood Brucellosis
Infection, 2002 The Th1/Th2 cytokine balance seems to be involved in the susceptibility or resistance to Brucella infection, however the precise role of interleukins in human brucellosis has not been thoroughly explored.The serum levels of interleukin-3 (IL-3) and interleukin-4 (IL-4) were measured by enzyme-linked immunosorbent assay (Quantikines, R&D Systems) in ...
Galanakis, E. +3 more
openaire +3 more sources
The role of interleukin-4 and interleukin-5 Th2 cytokines in assessing severity and prognosis of acute pancreatitis [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2021 Introduction/Objective. Acute pancreatitis (AP) is a relatively common disease which in most patients has favorable course. However, in approximately 20% patients, the course of the disease is more severe with high mortality (40–50%).
Doklestić Krstina +6 more
doaj +1 more source
Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]
, 2012 BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza +4 more
core +1 more source