Results 41 to 50 of about 1,050,624 (355)
Bisdemethoxycurcumin and Its Cyclized Pyrazole Analogue Differentially Disrupt Lipopolysaccharide Signalling in Human Monocyte-Derived Macrophages [PDF]
, 2018 open11noSeveral studies suggest that curcumin and related compounds possess antioxidant and anti-inflammatory properties including modulation of lipopolysaccharide- (LPS-) mediated signalling in macrophage cell models. We here investigated the effects of
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Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2020 Our research focused on the role of immune mechanisms in diabetic foot ulcers development and impaired healing. A 3D skin culture system, as a relevant skin model, has proved valuable in investigating these mechanisms and is a useful tool to study ...
Mashkova M. A. +2 more
doaj +1 more source
THE CHANGES IN THE LEVEL OF BETA ENDORPHIN, INTERSLEUKIN-2, INTERLEUKIN-4, INTERLEUKIN-6, IMUNOGLOBULIN AND CORTISOL HORMONE ON THE PRACTICES OF SATRIA NUSANTARA [PDF]
, 2010 The purpose of this research is to reveal the changes of immunity at breathing exercises. This is an experimental research study. This research used “randomized pretest-posttest control group design.
Sudarko, Rumpis Agus
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
Microglia M2A Polarization as Potential Link between Food Allergy and Autism Spectrum Disorders
Pharmaceuticals, 2017 Atopic diseases are frequently co-morbid with autism spectrum disorders (ASD). Allergic responses are associated with an activation of mast cells, innate lymphoid cells, and Th2 cells.
Hans O. Kalkman, Dominik Feuerbach
doaj +1 more source
ADAMTS -1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes [PDF]
, 2006 ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) enzymes are a recently described group of metalloproteinases. The substrates degraded by ADAMTS-1, -4 and -5 suggests that they play a role in turnover of extracellular matrix in the
A.K. Cross +52 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses
Frontiers in Immunology, 2019 Interleukin-4 (IL-4) receptor (IL-4R) signaling plays a pivotal role in type 2 immune responses. Type 2 immunity ensures several host-protective processes such as defense against helminth parasites and wound repair, however, type 2 immune responses also ...
Cecilie Egholm +4 more
doaj +1 more source
Interleukin-4/interleukin-4 receptor gene polymorphisms in hand osteoarthritis [PDF]
Osteoarthritis and Cartilage, 2010 IL-13/IL-4/IL-4R system has strong chondroprotective activity. We investigated polymorphisms in these genes as potential hand osteoarthritis (OA) susceptibility loci by performing a case-control association study.Eighteen common single nucleotide polymorphisms (SNPs) (nine in IL-4R, five in IL-4 and four in IL-13) were genotyped in 403 patients (380 ...
Vargiolu M. +11 more
openaire +4 more sources