The Intriguing Role of Interleukin 13 in the Pathophysiology of Asthma
Frontiers in Pharmacology, 2019 Approximately 5–10% of asthmatic patients worldwide suffer from severe asthma. Experimental and clinical studies have demonstrated that IL-13 is an important cytokine in chronic airways inflammation.
Giancarlo Marone +14 more
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Immune response to Leishmania (Leishmania) chagasi infection is reduced in malnourished BALB/c mice
Memorias do Instituto Oswaldo Cruz, 2010 Protein-energy malnutrition and micronutrient deficiencies may down-regulate immune response and increase morbidity and mortality due to infection. In this study, a murine model was used to study the effects of protein, iron and zinc deficiencies on the ...
Tiago Donatelli Serafim +4 more
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Impacts of BMI & IL-4 Genetic Polymorphisms (rs2243250 C/T & rs2227284 A/C) on Iranian Breast Cancer Patients: a Pilot Study [PDF]
Journal of Advanced Biomedical Sciences, 2022 Background & Objective: Breast cancer is a phenotypically complex and diverse genetic disease caused by changes in the structure and expression of specific genes. Immune system factors are also involved in the etiology of this neoplasm.
Samanehsadat Shahidi +1 more
doaj
Design of human interleukin-4 antagonists inhibiting interleukin-4-dependent and interleukin-13-dependent responses in T-cells and B-cells with high efficiency [PDF]
, 1994 Human interleukin-4 possesses two distinct sites for receptor activation. A signaHing site, comprising residues near the C-terminus on helix D, determines the efficacy of interleukin-4 signal transduction without affecting the binding to the interleukin ...
Reusch, P. +3 more
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Evaluating the Effect of Interleukin-4 in the 3xTg Mouse Model of Alzheimer’s Disease
Frontiers in Neuroscience, 2020 Chronic neuroinflammation has long been hypothesized to be involved in Alzheimer’s Disease (AD) progression. Previous research suggests that both anti-inflammatory and inflammatory microglia ameliorate amyloid pathology, but the latter worsen tau ...
Dawling A. Dionisio-Santos +3 more
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Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2020 Our research focused on the role of immune mechanisms in diabetic foot ulcers development and impaired healing. A 3D skin culture system, as a relevant skin model, has proved valuable in investigating these mechanisms and is a useful tool to study ...
Mashkova M. A. +2 more
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Interleukin-6 level in pediatric patients with COVID-19.
, 2023 Interleukin-6 level in pediatric patients with COVID-19.
Bahrul Fikri (17296062) +8 more
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Microglia M2A Polarization as Potential Link between Food Allergy and Autism Spectrum Disorders
Pharmaceuticals, 2017 Atopic diseases are frequently co-morbid with autism spectrum disorders (ASD). Allergic responses are associated with an activation of mast cells, innate lymphoid cells, and Th2 cells.
Hans O. Kalkman, Dominik Feuerbach
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, 2020 Median level of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10), interleukin-12p70 (IL-12p70), interleukin-17A (IL-17A), tumour necrosis factor alfa (TNF-α) and interferon gamma (IFN-γ) of ...
Robert Nowak (6748448) +1 more
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Indicators of cytokines in children with hepatobiliary pathology combined with parasitosis
Gastroenterologìa, 2018 Background. Hepatobiliary pathology (HBP) in children tend to continual growth, and the pathology itself is characterized by a group of features that are absent in adults.
T.V. Sorokman +2 more
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