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Site-specific articular responses to b/tsDMARDs in rheumatoid arthritis: a longitudinal observational study from the Swiss Clinical Quality Management Registry. [PDF]

RMD Open
Steimer A, Götschi A, Brändli J, Lauper K, Kyburz D, Möller B, Adler S, Förger F, Dan D, Brulhart Bletsas L, Timpert-Argust P, Andor M, Distler O, Micheroli R, Finckh A, Ospelt C, Ciurea A.   +16 more
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Guselkumab as a Treatment Adjunct for Pyoderma Gangrenosum While Maintaining Clinical Remission of Ulcerative Colitis. [PDF]

ACG Case Rep J
Moghe R, Mathew AJ, Choi D, Rubin DT.
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Metalloimmunotherapies: metal-driven regulatory networks in the immune microenvironment. [PDF]

Front Immunol
Wen B, Wu Y, Lian X, Li X, Xue B, Guo J.
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Inflammaging and Senescence-Associated Secretory Phenotype (SASP) in Psoriasis - A Narrative Review of Potential Mechanisms and Anti-Inflammaging Strategies. [PDF]

Psoriasis (Auckl)
Filipek K, Nowowiejska-Purpurowicz J, Flisiak I.   +2 more
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The plasticity and metabolic reprogramming of macrophage in ulcerative colitis. [PDF]

Front Immunol
Zhang Y, Yang D, Jiang J, Wang D, Ji F, Sun Z.   +5 more
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Neutrophil Extracellular Trap Formation-Derived Peptidylarginine Deiminases in the Citrullination of Oral Bacteria to Promote Inflammation in Rheumatoid Arthritis. [PDF]

J Rheumatol
Acharya S, Brewer RC, Gomez AM, Younis S, Pandit M, Jahanbani S, Sharpe O, Love ZZ, Howard MC, Orange DE, Robinson WH.   +10 more
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Establishment of a New Interleukin-6(IL-6) Receptor Inhibitor Applicable to the Gene Therapy for IL-6-Dependent Tumor

Establishment of a New Interleukin-6(IL-6) Receptor Inhibitor Applicable to the Gene Therapy for IL-6-Dependent Tumor
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Soluble gp130 is the natural inhibitor of soluble interleukin‐6 receptor transsignaling responses

European Journal of Biochemistry, 2001
Signal transduction in response to interleukin‐6 (IL‐6) requires binding of the cytokine to its receptor (IL‐6R) and subsequent homodimerization of the signal transducer gp130. The complex of IL‐6 and soluble IL‐6R (sIL‐6R) triggers dimerization of gp130 and induces responses on cells that do not express membrane bound IL‐6R.
T, Jostock, J, Müllberg, S, Ozbek, R, Atreya, G, Blinn, N, Voltz, M, Fischer, M F, Neurath, S, Rose-John   +8 more
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