Results 191 to 200 of about 689,003 (314)
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun +10 more
wiley +1 more source
The Role of Interleukin-8 (IL-8) in Treatment-Resistant Depression: A Review of Mechanisms, Biomarker Potential, and Therapeutic Implications. [PDF]
Lisowska KA.
europepmc +1 more source
A hybrid biomechanical–electromagnetic energy‐harvesting e‐skin is developed using a gelatin‐based outer matrix with a zwitterionic conductive inner layer. The e‐skin autonomously generates stable electrical stimulation from daily body motion and ambient electronics, enabling significantly enhanced wound healing bothin vitro and in vivo.
Syun‐Hong Chou +12 more
wiley +1 more source
(Front. Biosci., 10:853-865)The Role of Interleukin-8 in Cancer Cells and Microenvironment Interaction [PDF]
Yuan A, Chen JJW, Yao PL, Yang PC
core
High interleukin-8 serum levels independently predict long-term all-cause mortality in chronic heart failure. [PDF]
Traub J +8 more
europepmc +1 more source
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang +10 more
wiley +1 more source
Unveiling the anti-inflammatory potential of RF16, an interleukin 8-derived therapeutic peptide in macrophages. [PDF]
Chang CC +4 more
europepmc +1 more source
Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen +15 more
wiley +1 more source
Serum Concentrations of Interleukin-8 and Vitamin D Levels in Jordanian Patients with Rheumatoid Arthritis. [PDF]
Ali Deeb AS +4 more
europepmc +1 more source

