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Interleukin-18, interleukin-8, and CXCR2 and the risk of silicosis
Toxicology and Industrial Health, 2012Molecular mechanisms in the pathogenesis of silicosis are not fully understood. Exposure to crystalline silica leads to the activation of signaling pathways controlling the production and secretion of inflammatory mediators. Inflammatory cytokines are noted as important candidate genes for fibrotic lung diseases.
Iraj, Mohebbi +2 more
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Acta Obstetricia et Gynecologica Scandinavica, 2000
Background. The chemokine interleukin‐8 is present in a variety of tumor types with suggested effects on proliferation, migration, and angiogenesis. Elevated levels of interleukin‐8 are present in cyst fluids from malignant ovarian tumors. The origin and potential targets for this chemokine in ovarian tumors were investigated in this study.Methods ...
K, Ivarsson +4 more
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Background. The chemokine interleukin‐8 is present in a variety of tumor types with suggested effects on proliferation, migration, and angiogenesis. Elevated levels of interleukin‐8 are present in cyst fluids from malignant ovarian tumors. The origin and potential targets for this chemokine in ovarian tumors were investigated in this study.Methods ...
K, Ivarsson +4 more
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Neutrophil activation by monomeric interleukin-8
Cytokine, 1994Interleukin-8 (IL-8), a pro-inflammatory protein, has been shown by nuclear magnetic resonance (NMR) and x-ray techniques to exist as a homodimer. An IL-8 analog was chemically synthesized, with the amide nitrogen of leucine-25 methylated to selectively block formation of hydrogen bonds between monomers and thereby prevent dimerization. This analog was
K, Rajarathnam +6 more
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Interleukin-8 Synthesis and the Onset of Labor
Obstetrics & Gynecology, 1995To examine the role of cytokines in cervical dilation.In 55 patients undergoing cesarean delivery, we took samples from the lower uterine segment, the decidua, and the membranes. We determined the concentrations of interleukin (IL)-2, IL-8, tumor necrosis factor-alpha, matrix metalloproteinase (MMP)-8, and MMP-9 in the different tissues.Depending on ...
OSMERS, RGW +3 more
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Interleukin-8 in Acute Myeloid Leukemia
Blood, 1999To the Editor: In their recent report, Terui et al[1][1] describe the apoptotic activity exerted by endothelial interleukin-8 (IL-8) on a number of leukemic cell lines and in particular on K562 myeloid cells both in vitro and in vivo, in a mouse experimental model. The report by Terui et al[1][1]
VINANTE, Fabrizio +3 more
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Interleukin-8 in cancer pathogenesis, treatment and follow-up.
Cancer Treatment Reviews, 2017C. Alfaro +9 more
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Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.
Advances in Immunology, 1994M. Baggiolini, B. Dewald, B. Moser
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Immuno-analyse & Biologie Spécialisée, 1990
P Mathelier-Fusade, F Delers, R Engler
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P Mathelier-Fusade, F Delers, R Engler
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