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Neutrophil activation by monomeric interleukin-8
Cytokine, 1994Interleukin-8 (IL-8), a pro-inflammatory protein, has been shown by nuclear magnetic resonance (NMR) and x-ray techniques to exist as a homodimer. An IL-8 analog was chemically synthesized, with the amide nitrogen of leucine-25 methylated to selectively block formation of hydrogen bonds between monomers and thereby prevent dimerization. This analog was
K, Rajarathnam +6 more
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Interleukin-8 in Acute Myeloid Leukemia
Blood, 1999To the Editor: In their recent report, Terui et al[1][1] describe the apoptotic activity exerted by endothelial interleukin-8 (IL-8) on a number of leukemic cell lines and in particular on K562 myeloid cells both in vitro and in vivo, in a mouse experimental model. The report by Terui et al[1][1]
VINANTE, Fabrizio +3 more
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Interleukin-6 and Interleukin-8 in Newborn Bacterial Infection
American Journal of Perinatology, 2001The objective of this study is to determine the plasma concentrations and diagnostic accuracy of interleukin-6 (IL-6) and interleukin-8 (IL-8) in newborn infection. One hundred and one newborn infants with clinical signs of infection during their primary hospitalization were investigated with the minimum of a blood culture, C-reactive protein (CRP ...
Mehr, Sam S. +4 more
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Interleukin 8 production and interleukin 8 receptor expression in human myometrium and leiomyoma
American Journal of Obstetrics and Gynecology, 2001Interleukin 8 is a potent chemoattractant cytokine that is expressed in a variety of human tumors and is known to induce mitogenesis. We aimed to investigate the production of interleukin 8 and the expression of its receptor in myometrium and leiomyoma, in which we hypothesized that interleukin 8 may contribute to cellular proliferation.Myometrial and ...
L M, Senturk +3 more
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Journal of Urology, 2000
Studies have demonstrated that the pro-angiogenic cytokine interleukin-8 (IL-8) and the IL-8 receptors likely have a role in the growth and metastasis of various solid tumors. We hypothesized that in vivo neuroblastoma expresses IL-8 and the IL-8 receptors A and B, and that factors known to regulate IL-8 expression are present and active in the ...
F A, Ferrer +6 more
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Studies have demonstrated that the pro-angiogenic cytokine interleukin-8 (IL-8) and the IL-8 receptors likely have a role in the growth and metastasis of various solid tumors. We hypothesized that in vivo neuroblastoma expresses IL-8 and the IL-8 receptors A and B, and that factors known to regulate IL-8 expression are present and active in the ...
F A, Ferrer +6 more
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Interleukin-8 in cancer pathogenesis, treatment and follow-up.
Cancer Treatment Reviews, 2017C. Alfaro +9 more
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Allergie und Immunologie, 1991
Interleukins are well defined biologically active factors serving the intercellular communication. Here is given a review on the interleukins 1-8.
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Interleukins are well defined biologically active factors serving the intercellular communication. Here is given a review on the interleukins 1-8.
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Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.
Advances in Immunology, 1994M. Baggiolini, B. Dewald, B. Moser
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