Interleukins changes in blood of non-ethanol liver damage rats of different sex
Non-alcoholic liver disease is associated with liver injury, such as steatosis, steatohepatitis, fibrosis and cirrhosis. During their development, inflammation is occure and organs damage develops by help of cytokines influences. The intensity of injury
O. Denefil, О. Bolyukh
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Role of genetic aspect in pathogenesis of atopic dermatitis [PDF]
The pathogenesis of atopic dermatitis (AD) is a very complicated process that involves an intricate array of molecules. Nowadays it is generally accepted that cytokines play an important role in the progression of the clinical presentation of atopic ...
Wesserling Martyna
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Mechanisms altering airway smooth muscle cell Ca(2+) homeostasis in two asthma models [PDF]
Background: Asthma is characterized by airway remodeling, altered mucus production and airway smooth muscle cell (ASMC) contraction causing extensive airway narrowing. In particular, alterations of ASMC contractility seem to be of crucial importance. The
Bergner, Albrecht+6 more
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Causal analysis between altered levels of interleukins and obstructive sleep apnea
BackgroundInflammation proteins including interleukins (ILs) have been reported to be related to obstructive sleep apnea (OSA). The aims of this study were to estimate the levels for several key interleukins in OSA and the causal effects between them ...
Minhan Yi+15 more
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IL-13R alpha 2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca2+ signaling [PDF]
Background: The interleukins IL-4 and IL-13 play a key role in the pathophysiology of asthma. The interleukin receptor IL-13R alpha 2 is believed to act as a decoy receptor, but until now, the functional significance of IL-13R alpha 2 remains vague ...
Bergner, Albrecht+5 more
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Differential expression of IL-17, 22 and 23 in the progression of colorectal cancer in patients with K-ras mutation: Ras signal inhibition and crosstalk with GM-CSF and IFN-γ. [PDF]
Recent studies have suggested that aberrant K-ras signaling is responsible for triggering immunological responses and inflammation-driven tumorigenesis.
Savvas Petanidis+4 more
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The Relationship Between Serum Levels of Interleukins 6, 8, 10 and Clinical Outcome in Patients With Severe Traumatic Brain Injury [PDF]
Background: Clinical outcome in patients with severe traumatic brain injury (TBI) depends on both primary and secondary brain injuries. Neuroinflammation is an important secondary mechanism, which occurs by releasing interleukins (ILs).
Dehnadi Moghaddam, A.+7 more
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Interleukins in lacrimal fluid and diabetic retinopathy
The leading role of diabetic retinopathy is considered the main causal factor of decreased visual acuity in the able-bodied and elderly ages determines its clinical relevance, including immunological aspects of pathogenesis to improve the diagnosis and ...
I. V. Lev, N. M. Agarkov
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European Sea Bass (Dicentrarchus labrax) immune status and disease resistance are impaired by arginine dietary supplementation [PDF]
Infectious diseases and fish feeds management are probably the major expenses in the aquaculture business. Hence, it is a priority to define sustainable strategies which simultaneously avoid therapeutic procedures and reinforce fish immunity.
A Nomura+57 more
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Cellular interactions in the tumor microenvironment: the role of secretome [PDF]
Over the past years, it has become evident that cancer initiation and progression depends on several components of the tumor microenvironment, including inflammatory and immune cells, fibroblasts, endothelial cells, adipocytes, and extracellular matrix ...
Castelo-Branco, Pedro+6 more
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