Results 21 to 30 of about 555,638 (360)
International Journal of Molecular Sciences, 2022 Mast cells play a critical role in inflammatory diseases and tumor growth. The versatility of mast cells is reflected in their ability to secrete a wide range of biologically active cytokines, including interleukins, chemokines, lipid mediators ...
Antonio Giovanni Solimando +2 more
semanticscholar +1 more source
Journal of Leukocyte Biology, 1997 Abstract Interleukin 16 (IL-16) was initially described in 1982 as the first T cell chemoattractant. Through interaction with CD4, IL-16 has now been characterized as a chemoattractant for a variety of CD4+ immune cells. Recent in vivo studies have more fully characterized IL-16 as an immunom odulatory cytokine that contributes to the ...
W W, Cruikshank +2 more
openaire +3 more sources
Acta Biomedica Scientifica, 2023 Background. The development of diabetic retinopathy is favoured by immunological factors such as interleukins (IL) and chemokines. However, analysis of blood interleukins in patients aged 45–59 years with diabetic retinopathy in type 2 diabetes mellitus,
I. V. Lev, N. M. Agarkov, A. E. Kopylov
doaj +1 more source
Biological Role, Mechanism of Action and the Importance of Interleukins in Kidney Diseases
International Journal of Molecular Sciences, 2022 Each year, the number of patients who are diagnosed with kidney disease too late is increasing, which leads to permanent renal failure. This growing problem affects people of every age, sex and origin, and its full etiopathogenesis is not fully ...
Paulina Mertowska +3 more
semanticscholar +1 more source
The Role of Interleukins in the Pathogenesis of Dermatological Immune-Mediated Diseases
Advances in Therapy, 2022 Autoimmune inflammatory diseases are primarily characterized by deregulated expression of cytokines, which drive pathogenesis of these diseases. A number of approved and experimental therapies utilize monoclonal antibodies against cytokine proteins ...
I. Turchin, M. Bourcier
semanticscholar +1 more source
Interleukin-7 and Interleukin-15 for Cancer [PDF]
Journal of Cancer, 2014 Interleukin 7 and 15 are considered powerful pro-inflammatory cytokines, they have the ability to destabilize chromosomes and induce tumorigenesis. Additionally, they can control malignancy proliferation by influencing the tumor microenvironment and immune system. Immunotherapy has been proposed as a treatment modality for malignancy for over a decade;
Zarogoulidis, P. +16 more
openaire +2 more sources
Evaluation of Some New Cytokines in Rheumatoid Arthritis
مجلة كلية الطب, 2022 Background: Cytokines have an essential contribution to the inflammatory response and the development of chronic inflammation. Therefore, it has a pivotal role in the pathogenesis of rheumatoid arthritis (RA). Interleukins are closely related to RA, and
Zahra'a A. Ahmed
doaj +1 more source
Genes, 2021 Understanding the evolution of interleukins and interleukin receptors is essential to control the function of CD4+ T cells in various pathologies.
Norwin Kubick +8 more
semanticscholar +1 more source
Proceedings, 2020 Interleukins proved to be valuable biomarkers for different diseases. Interleukins 1β, 6, and 12 can be used as biomarkers for brain cancer diagnosis, and therefore this paper proposed a needle stochastic sensor based on protoporphyrin IX immobilized in ...
Sorin Sebastian Gheorghe +3 more
doaj +1 more source